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Explain why the coronavirus is so deadly in patients with diabetes

2020-09-23T10:20:11.973Z


In Argentina it is the most frequent comorbidity in deaths from Covid-19 under 60 years of age.Vanesa Lopez 09/22/2020 - 23:27 Clarín.com Society During the annual meeting of the European Association for the Study of Diabetes (EASD), evidence was presented of the “devastating” impact that the new coronavirus is having on people with diabetes. The alert is also lit in Argentina, where this disease is the most frequent comorbidity in deaths from Covid-19 under 60 years of age. "The main ri


Vanesa Lopez

09/22/2020 - 23:27

  • Clarín.com

  • Society

During the annual meeting of the European Association for the Study of Diabetes (EASD), evidence was presented of the “devastating” impact that the new coronavirus is having on people with diabetes.

The alert is also lit in Argentina, where this disease is

the most frequent comorbidity

in deaths from Covid-19 under 60 years of age.

"The main risk factors for mortality (from Covid-19) include old age and chronic conditions, in particular obesity, diabetes, hypertension, heart and kidney disease," said Professor Juliana Chan, from the University China from Hong Kong, in charge of the presentation.

A recent report published in

The Lancet Diabetes & Endocrinology

, based on a survey conducted in the United Kingdom, concluded that among 23,698 deaths due to Covid-19,

30% occurred in people with diabetes

.

Taking into account multiple risk factors, such as age, ethnicity and the presence of other chronic conditions, people with type 1 diabetes had

almost three times the

risk of death

and those with type 2 diabetes

almost two times greater

risk

of dying by Covid-19 compared to those without the disease.

Patient with Covid-19 and diabetes prepares to be transferred to a hospital in Mexico City.

Photo Reuter.

Despite the short duration of the pandemic, less than a year, a search of the terms "Covid-19 and diabetes" returns some

1,800 scientific publications

on the PubMed platform.

"Many of these reports indicated close relationships between high blood glucose levels and

poor outcomes

, including mechanical ventilation, intensive care unit admissions, and death of Covid-19 patients," says Chan.

Glucose is a fuel and its efficient use depends on the adequate supply of oxygen and the action of insulin to promote the entry of glucose into cells to maintain body functions and survival.

Diabetes is due to an

absolute or relative

insulin insufficiency

.

People with poorly controlled diabetes have low inflammation, poor circulation, and body defenses.

During acute stress such as Covid-19, these interconnected systems

can become destabilized,

leading to uncontrolled blood glucose and multi-organ failure.

In a consensus statement published in

The Lancet Diabetes & Endocrinology

, international experts called for

optimization of hospital and outpatient care

, including the appropriate use of insulin to control blood glucose and the use of organ-protective medications to improve the outcomes of these high-risk patients.

The situation in Argentina

Consulted by

Clarín

, Dr. Gabriel Lijteroff, Head of Diabetology at the Santamarina Hospital and director of the scientific committee of the Argentine Diabetes Federation (FAD), explains that when people with diabetes develop a viral infection it can be

more difficult to treat

due to fluctuations in blood glucose levels.

"For this reason,

adequate glycemic control

is always an indispensable tool in the prevention of complications," says Lijteroff.

The expert shares data published in August in the Argentine Journal of Public Health, based on the first 116,974 cases of Covid-19 in our country.

The report shows that arterial hypertension was the most reported comorbidity in confirmed cases of Covid-19 (15.8%) and in deaths over 60 years (58.7%).

Proper glycemic control is essential for people with diabetes.

Photo DPA.

However,

in the deceased under 60 years of age, the most frequent comorbidity was diabetes.

Three out of ten (29.9%) of the "young" deaths from Covid-19 had this disease. 

In addition,

8.4% of confirmed

Covid-19 cases in Argentina

had diabetes

, surpassing other comorbidities such as asthma (5.6%), obesity (5.3%) and heart failure (2.7 %).

As for those over 60 years of age, the figure rises to 22.4% of those infected.

Another problem that Lijteroff raises - based on different publications - is that people who

debut with diabetes were reported

in the context of the coronavirus disease.

"In other words, a direct condition of the coronavirus has been seen, producing inflammatory processes at the pancreatic level," he says.

"In turn, the coronavirus has determined greater fluctuations in blood glucose in people with diabetes.

That is, a worse metabolic control in the context of hospitalization.

For this reason, it has been seen that those who have been infected have a better prognosis if, prior to their coronavirus disease, they

had good control of their blood glucose

”, Lijteroff closes.

Recommendations for people with diabetes

The “disaster committee” of the International Diabetes Federation for South and Central America (IDF-SACA) - led by Dr. Lijteroff - shares several recommendations for people with diabetes.

* Respect social isolation.

It is the most efficient strategy in the prevention of contagion by coronavirus.

* Strictly comply with medical recommendations

, respecting the established guidelines regarding physical activity, food plan and drugs.

* Good metabolic control

facilitates medical treatment in case of contracting coronavirus disease.

Respecting social isolation is the most efficient strategy to prevent contagion by coronavirus.

Photo Xinhua.

* Make sure you have enough medicines and supplies on time.

Being connected with associations dedicated to the care of diabetes and people with the same condition is a valuable strategy in case of delays or logistical problems in the usual provision.

* Have on hand sugary products

, such as honey, jams, packaged juices, regular sodas, sugary sweets to deal with hypoglycemia.

* Establish with the treating health team

what circumstances warrant attending hospital institutions or calling for home medical services, according to the recommendations of each country.

* Be attentive and abide by the recommendations

issued by the competent authorities.

It is to be expected that they will be very dynamic, according to how the infection develops in each place.

$

Look also

Patient groups come together to complain about the lack of access to treatments caused by the coronavirus

The Pan American Health Organization warned of the "devastating impact" of the pandemic on other diseases

Source: clarin

All life articles on 2020-09-23

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