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Britain has already approved a vaccine for Corona - who is next in line?
There is talk of a third closure in Israel, but the world continues to march with determination towards the Corona vaccine.
Immunologist Dr. Erez Gerti concludes a week - which began and even ended with good news - with the scientific race to eradicate the corona
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Vaccine for corona
Vaccine
Corona
Corona virus
Dr. Erez Gerty
Friday, 04 December 2020, 13:56
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In the video: The British Minister of Health expresses satisfaction with the approval for the use of the Pfizer vaccine (Photo: Reuters, edited by Tal Reznik)
This week started with good news and ended with equally good news.
On Monday, a modern company released an update to its interim results on the third phase of the clinical trial of the vaccine it is developing.
The company said it had collected data from 196 patients infected with the epidemic corona virus SARS-CoV-2, from the 30,000 volunteers who received the real vaccine or the placebo vaccine given to the control group.
185 of the patients were in the control group and only 11 were vaccinated with the real vaccine, so its effectiveness is now estimated at 94.1 percent.
Moreover, none of those who received the real vaccine became seriously ill.
It is important to note that the number of vaccinated people who have suffered from the disease is not large, so the figure may still vary.
Anyway, this is definitely encouraging news.
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Modern, too, has joined its prominent competitor, Pfizer, and submitted the vaccine it is developing for emergency approval by the US Food and Drug Administration (FDA).
A hearing on their vaccine is set for Dec. 17, a week after the Pfizer vaccine hearing.
Ironically, the high infection rate of the virus, which has made the disease a global epidemic (pandemic), is also what makes it possible to expedite the approval of vaccines against it.
In contrast to clinical trials conducted on vaccines against other pathogens, rapid infection soon led to a large enough number of infections to provide a reasonable estimate of vaccine efficacy, at a level that allows it to be submitted for approval.
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On Thursday, we saw a play we had not seen in a long time - results that did not come out as a press release but were published in a peer-reviewed journal and not just in the New England Journal of Medicine.
The study examined the effectiveness of Moderna vaccine for four months from the first dose.
In the vaccine they continued to monitor the 34 first-stage volunteers and measured the levels of antibodies in the blood for four months and saw that they were still high and that the antibodies were still able to neutralize the virus in the laboratory.
This is excellent news that indicates that the vaccine is effective although it is not yet possible to estimate the duration of the immune memory.
Although Modern has approached emergency clearance but the experiments are still ongoing and continue to monitor the volunteers in order to continue to evaluate the safety and efficacy of the vaccine over time.
Why has the UK already confirmed?
On the other side of the Atlantic, the British Ministry of Health announced on Wednesday that it is not waiting for an FDA decision and immediately issues an emergency permit for Pfizer's vaccine.
Thus, the inhabitants of the United Kingdom will soon begin to be vaccinated in it.
This step does not necessarily indicate a less rigorous examination, because it is basically a data analysis of a not very complex experiment.
British Prime Minister Boris Johnson at AstraZenica Corona Vaccine Factory (Photo: Reuters)
However, the European Food and Drug Administration (EMA) sharply criticized the British, claiming that they had not tested the vaccine on the basis of sufficient data and were in too much of a hurry to approve it.
The British, for their part, replied that they met all the strict standards.
Perhaps the reason for the British rapid action was their desire to secure for themselves the first doses of the vaccine, before fierce competition began between the countries of the world for the vaccine doses already produced.
In the meantime, most of the other health authorities seem to be waiting to see what happens at the U.S. Food and Drug Administration hearing next week, and if he approves the vaccine, there will likely be a wave of approvals for that vaccine around the world.
The largest vaccination campaign in the world
The logistical preparations for the vaccine operation, one of the largest known to the world, are already in full swing.
In the United States, a pilot of a deep-freeze transport package to four countries was piloted two weeks ago, and this week it was confirmed that the first shipment was already packaged and ready to make its way from a plant in Belgium to the United States once the vaccine was approved.
The shipping conditions of the Pfizer vaccine are particularly complex, as it must be stored at a temperature of 70 degrees Celsius below zero, which will require the use of special freezers and lots of dry ice.
Another concern that has arisen recently is that criminal organizations will try to disrupt the vaccination campaign or sell stolen or counterfeit vaccines online.
Interpol even issued a special warning this week against this scenario.
To read a summary of the previous weeks in the scientific race to eradicate the corona
Dr. Erez Gerti is an immunologist at the Davidson Institute for Scientific Education
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