Mainly intended for women, progesterone derivatives are indicated in the treatment of endometriosis and infertility but also as contraceptives, in menstrual disorders or even to support women towards menopause. However, since 2010, several hundred cases of meningiomas, a form of benign brain tumor, have been attributed to prolonged use of this type of treatment. Measures to restrict access to these molecules were put in place in France, while at the same time studies were carried out to measure the extent of the problem. The latest results appear this Thursday in the
BMJ
.
In this work carried out by EPI-PHARE, the scientific interest group made up of the ANSM and the National Health Insurance Fund (Cnam), an expert committee calculated the individual excess risk of around ten progestins, including those already incriminated (Androcur, Lutéran and Lutényl). They thus revealed that three molecules…
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