Study reveals: there are two ways to die from corona - crucial finding for treatment?

Pathologists have autopsied Covid 19 victims and gained important insights.

These could enable more successful treatment of patients.

• The study

  "Molecular profile of a killer"

  provides important information on a fatal course of

  Covid-19 disease

  .

• There are two ways

  to die

  from

  Covid-19 *

  .

• The new knowledge can now be applied in the treatment of

  Covid 19 patients

  .

Liestal -

.

It sounds like the title of a new crime novel that will soon be in bookstores.

In fact, it is the summary of a study on the fatal effects of

in the body.

It was published in the science

magazine

.

The last author of the work -

in

- has now

commented

on the findings.

The molecular pathologist is one of the first to

autopsies on

victims.

She told

online that at the beginning of the

“they had absolutely no idea what to expect.

"It was a completely new situation for us

to investigate

victims of this

." However, as the results of the study now show, the examinations were urgently needed.

Between March and May, Mertz and her colleagues carried out and evaluated a total of 21 autopsies.

The autopsied victims were mostly high-risk patients (male, older than 70 and with previous illnesses).

Transcriptomic, histologic and cellular profiling of post-mortem # COVID19 lung tissues revealed 2 patterns of immune responses.

https://t.co/3hWIOZPdVI Study led by @TobiasJunt and Kirsten Mertz with @YariCiani @ViktorKoelzer Ronny Nienhold 1/3

- Francesca Demichelis (@FrancescaBZNY) June 19, 2020

During the complex autopsies,

could be identified very quickly

.

On the one hand, there were deceased who showed severe damage, especially in the lungs, and on the other,

who showed only minor organ damage.

This finding is amazing because it shows that people who contracted the same

died from different consequences.

The study shows that one group of victims had a high viral load in the lungs with little damage at the same time.

The other group, however, had little or no virus in their lungs.

In return, the lung damage was enormous.

The course and duration of the

were therefore different in the two identifiable groups.

Coronavirus: There are two ways to die from Covid-19

In an interview with

ONLINE, Mertz stated that the group of patients who had a high viral load in the lungs

shortly after the

because the

unable to fight

the

successfully.

In the case of the

the other group, the immune system was

good at fighting

the

.

However, in this case, those affected died a little later from the

caused by an overreaction of the

.

Covid-19: Increased blood clotting as a risk factor for severe organ damage

In the two groups, however, it is not a question of two fundamentally different

but of one course of the disease - only some patients died earlier than others.

The

not yet been able to find out

the reason for this

.

Only one connection was noticed: the group in which severe

found had increased

, which led to clots.

This was not the case in the other group.

The findings of the study

are

of great importance

in relation to the fight against the

.

This is because there are ideas for different

for patients with severe

.

In patients with a high viral load in the lungs, antivirals would have to be used first.

In the later phase of the disease, in which there can be an overreaction, on the other hand, special anti-inflammatory drugs would have to be used, which prevent an overreaction of the immune system and thus prevent the occurrence of tissue damage.

Coronavirus: "The virus was and is a killer"

Another important finding could be drawn from the study: a high viral load is particularly risky.

According to Mertz, a high virus load, especially in the risk group, could considerably worsen the course.

That's why

.

You may have a

may not completely prevent, but it reduces the recorded viral load during infection.

Mertz does not see

any difference to the current victims of

. She told Focus ONLINE that the virus has not changed much: "

." It is therefore important to bear in mind that people who do not belong to the risk group can also suffer from a severe course of the disease .