Jannik Sinner will start again for his climb to the world top 10 from the Masters 1000 in Miami and the draw has placed him in the part of the draw dominated by Carlos Alcaraz.
The Spaniard beat the blue in the semifinals at Indian Wells to then win the title against Medvedev and will want to repeat himself in Florida, where if all goes well for both they will find themselves on the penultimate step again.
Sinner will enter the game directly in the second round against the winner of the match between the Serbian Laslo Djere and a qualifier.
Among the other four Azzurri registered for the tournament, Fabio Fognini is also in the top half of the draw but will start from the first round against the French Constant Lestienne, n.60 in the ranking.
A possible derby with Sinner would take place in the third round.
In the other area, chaired by No. 3 Atp Stefanos Tsitsipas, there are Lorenzo Sonego, Matteo Berrettini and Lorenzo Musetti.
The Turinese has a complicated first round with the Austrian Dominic Thiem, while Berrettini will debut in the second round against the Colombian Daniel Elahi Galan or the American Mackenzie McDonald.
Finally, the Tuscan Musetti awaits the winner of the match between the Argentine Federico Coria and the Czech Jiri Lehecka in the second round.
There are also five Italians in Miami: Martina Trevisan, Camila Giorgi, Elisabetta Cocciaretto, Jasmine Paolini and Lucia Bronzetti.
The first will enter the field in the second round, against the winner between the Montenegrin Danka Kovinic and a qualifier.
Cocciaretto will be opposed to the Ukrainian Marta Kostyuk, winner on hard courts in Austin three weeks ago.
Camila Giorgi will find the Estonian Kaia Kanepi, with the prospect of facing the Belarusian Victoria Azarenka.
Debut against a qualifier for Paolini, while Lucia Bronzetti will debut against the Czech Linda Noskova.