05/09/2021 3:47 PM
Clarín.com
Society
Updated 05/09/2021 3:47 PM
The advancement of the second wave of coronavirus is directly linked to the appearance and development of new lineages of SARS-CoV-2.
In Argentina, the cases of the variants of the
United Kingdom and Manaus are
growing
, according to the latest report from the PAIS Project, dependent on the Ministry of Science, Technology and Innovation of the Nation.
The study comprised a total of 1,848 samples from the City and the provinces of Buenos Aires, Córdoba, Neuquén, Santa Fe, Río Negro, Mendoza, San Luis and Entre Ríos.
Hence, there was an
increase in the frequency
of detection of the variants 501Y.V1 (United Kingdom), 501Y.V3 (P.1, Manaus) and for the L452Q mutation without epidemiological link with tourism abroad between the beginning of March to end of April.
In the AMBA, there was a frequency of
27.1%
(CABA) and
12.8%
(GBA) for the UK variant;
31.3%
(CABA) and
31.9%
(GBA) for the 501Y.V3 variant of Manaus;
and
33.3%
(CABA) and
48.9%
(GBA) for the L452Q mutation compatible with the C.37 lineage.
The latter is known as the Andean variant, which would have originated in Peru.
Due to the new variants of the coronavirus, serious cases that demand hospitalization in intensive care are growing.
Photo: EFE
So far, the mutation combination characteristic of the South African variant has not been detected, it was reported.
"By mid-April it was observed that more than 90% of the SARS-CoV-2 viruses that circulated in the AMBA have
mutations in the Spike protein
that differentiate them from the viruses that circulated in the first wave," it was explained.
The report highlights that the Manaus variant was detected in
Greater La Plata
in
70.7%
of the cases analyzed, while in Mar del Plata it was 42.9% of infections.
The city of
Tandil
presented 62.5% of the cases associated with the UK variant.
In the provinces
On the other hand, in
San Luis
the Manaus variant was detected in 46.6%;
and in
Entre Ríos
a predominance of this variant was also observed, in 58.3% of the cases, in individuals with no history of traveling abroad or epidemiological link with travelers.
In
General Alvear
, in
Mendoza
, all the cases analyzed correspond to the Manaus variant, although "this outbreak is associated with the re-entry of a tourist contingent of local residents," it was specified.
In Mendoza, all the cases detected in the city of General Alvear were due to the Manaus variant.
Photo: Los Andes
In turn, in the province of
Santa Fe
, two cases of variant 501Y.V3 (Manaus) and one case of variant 501Y.V1 (United Kingdom) were detected in individuals without a history of traveling abroad or close contact with travelers .
In
Córdoba
, two cases of the 501Y.V3 variant (P.1, Manaus) were detected in individuals with a travel history and seven cases of the 501Y.V1 variant (United Kingdom), two of them with a travel history to Mexico and five acquired in the community.
Finally, in the province of
Neuquén
, a case of variant 501Y.V3 (Manaus) was detected in a temporary local worker.
"Active surveillance of the SARS-CoV-2 variants carried out made it possible to determine the presence of four variants of worldwide epidemiological interest in our country: the 501Y.V1 variant (United Kingdom), the 501Y.V3 variant (P.1 lineage, Manaus), variant P.2 (Rio de Janeiro) and variant CAL.20C (California, lineages B.1.427 and B.1.429), and allowed the detection of a lineage of increasing regional importance, lineage C.37 " , was highlighted.
Who relieves him
The PAIS Project was created by the Ministry of Science, Technology and Innovation of the Nation, the Inter-institutional Consortium for the Sequencing of the genome and genomic studies of SARS-CoV-2.
It is made up of research groups from different institutions with the aim of sequencing the genome and carrying out other genomic studies of SARS-CoV-2.
Coordinated by Dr. Mariana Viegas from the Ricardo Gutiérrez Children's Hospital Virology Laboratory, the team works jointly and collaboratively to carry out genomic studies of SARS-CoV-2 in our country and contribute both to local knowledge and to the global circulation database. viral GISAID (Global Initiative on Sharing All Influenza Data).
With information from Télam
DD
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