Fighting ovarian cancer: New study gives hope – mRNA active ingredient kills tumors. Every year thousands of women in Germany develop ovarian cancer - and thousands die from it.
The p53 gene is mutated in 96 percent of patients with ovarian cancer. This gene contains the instructions for a protein that normally detects damage in the cell's DNA and triggers repair mechanisms. However, in women affected by ovarian cancer, the mRNAs have errors, as does the gene from which they were copied. The researchers have now developed an mRNA in the laboratory with a blueprint for a flawless protein.