Fighting ovarian cancer: Study gives hope – mRNA active ingredient can kill tumors. Every year in Germany around 7,300 women suffer from ovarian cancer.
The p53 gene is mutated in 96 percent of patients with the cancer. Researchers have now developed an mRNA in the laboratory with a blueprint for a flawless protein. This artificial mRNA was packaged in fatty vesicles and brought together with cultures of human cancer cells. After treatment, these shrank and even began to die. The mRNA was also tested on mice and the tumors in the ovaries almost completely disappeared.