Hypothyroidism: Be careful when taking medication with coffee. Thyroid hormones should not be taken with coffee, according to Dr.

Wolfgang Wesiack. Women who take T4 every morning with coffee instead of water have lower T4 levels in their blood. Patients with thyroid disease should also not take their hormone tablets with milk or mineral water, as the amounts of calcium they contain can interfere with the absorption of thyroxine in the body. For this reason, patients should definitely adhere to the recommendation to use water – and not coffee – as the ingestion fluid.