According to the Halacha, is it permissible to operate the Iron Dome system? - Walla! Judaism. Rabbi Shai Tahan, head of the Sha'ari Ezra community and head of Beit Erzi HaLebanon, answers questions asked in the Beit Midrash and outside of it.
Many times the missile is already above the skies of a place where there are people, so the remains of the intercepted missile with the iron dome may fall on top of those people and injure them.