High cholesterol gene turned off, successful in mice tests - Biotech. Thanks to a new technique, it was possible to 'turn off' the gene responsible for high cholesterol in mice without modifying the DNA sequence.
The effect remained active for about a year, that is, until the The experiment was not completed. This is the first evidence of the long-term effectiveness of this technique and the strategy could also be useful for other diseases. The researchers concentrated their efforts on the Pcsk9 gene, which is involved in the regulation of cholesterol levels in the blood.