Trieste is also part of the LISA mission in search of gravitational waves. LISA satellites will follow the Earth in its orbit around the Sun, forming an equilateral triangle in space.

The configuration will allow a precise exchange of laser beams between the spacecraft. The lasers will reveal, thanks to minute variations in the distance between the satellites, the passage of gravitational Waves. The mission will also test the validity of Einstein's theory of General Relativity "with unprecedented accuracy" with "strong gravitational fields and speeds close to that of light"