Leicester City is the most prominent relegated team from the Premier League. Southampton and Leeds United will also have to compete in the Championship again.

After 91 years in LaLiga, Espanyol Barcelona were relegated to the second division for the first time in 2020. After eleven years in Serie A, Genoa's Sampdoria return to Serie B, where they last competed in the 2011/2012 season. The third relegation spot is between Hellas Verona and Spezia Calcio on the last matchday.