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Is there a part of our body that is resistant to corona?
The ways of infection of the corona are still being studied, but at the moment it can be said with certainty that the common way of infection is through drops and contact with carriers.
New research suggests that there may be one really small part of our body that manages to stop the development of the virus
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Thursday, 05 November 2020, 07:05
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Although we have been in the corona event for almost a year, the truth is that scientists still do not know exactly how the SARS-CoV-2 virus works.
The CDC's official directive says that the main way for the virus to spread is through breathing drops or small particles, which are emitted from the mouth or nose of infected people, and then inhaled by others.
But this is not the only way the virus is circulating.
Those same droplets and contagious particles can land on surfaces and pass through contact - meaning contagion can be caused if you touch something with virus particles on it, and then touch your mouth, nose or eyes, the CDC says.
However, new evidence suggests that at least part of the eye may be resistant to SARS-CoV-2 - even if it is susceptible to other types of viruses.
In a new study, researchers at the University of Washington in St. Louis found that the cornea - the transparent dome in front of the eye that covers the iris and pupil - was found to be resistant to coronavirus infection in experiments.
And yet, think of emphasizing that the findings are only preliminary.
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"Our findings do not prove that all corneas are durable," says molecular microbiologist Jonathan J. Miner, author of the study, published in the journal Cell Reports.
"But each donor cornea we tested was resistant to the corona virus. A subset of people may have a cornea that supports the growth of the virus, but none of the corneas we tested supported the growth and replication of SARS-CoV-2."
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In experiments using corneal tissue from 25 human donors as well as mouse corneas, the researchers exposed the eye tissue to three separate viruses: SARS-CoV-2, the affinity virus, the herpes simplex virus 1 (HSV-1, which mainly causes sores in the mouth).
What is in the cornea that stops the duplication of the virus?
Corona virus (Photo: Giphy)
In the human corneal test (which also contained conjunctival tissue, the membrane that covers the rest of the front of the eye), the experiment showed that herpes and affinity virus were able to replicate in the tissue - but tests showed no evidence of duplication of the SARS-CoV-2 virus.
"Coronary and conjunctiva are known to have receptors for the corona virus, but in our studies we found that the virus did not replicate in the cornea," says Regendra S. Apta, an ophthalmologist who participated in the study.
"Our data show that the new corona virus is unable to penetrate the cornea."
As for how the human cornea and conjunctiva are able to resist SARS-CoV-2, the team is not entirely sure.
It is estimated that a potential molecular inhibitor of viruses in the eye - known as interferon lambda - was able to limit the growth of the virus in the human cornea to the herpes virus or affinity, but the protein block did not appear to increase SARS-CoV-2's ability to replicate.
"It's important to respect what this virus is capable of doing."
Researchers currently estimate that human corneal resistance to the corona virus "apparently works in a distinctly antiviral pathway."
Exactly what this route is we do not yet know, and the team says further research is needed to confirm these findings.
In other words, healthcare professionals still do not have to throw away their goggles, and until we know otherwise, no one should assume that the corona virus cannot enter the body through the eyes, despite the apparent resistance of the cornea.
"It is important to respect what this virus is capable of doing and to take appropriate precautions," says Miner.
"We may learn that eye blinds are not necessary to protect against infection in the general community, but our research is really just the beginning."
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