Borussia Dortmund sacked Lucien Favre in the aftermath of the heavy defeat against Stuttgart (1-5).
Until the end of the season the team is entrusted to 38-year-old Edin Terzic, Favre's deputy.
"We are all grateful to Lucien Favre for his excellent work during the two and a half years" during which he coached the club, said BVB manager Hans-Joachim Watzke.
The new coach has already started preparations for Tuesday night's Bundesliga away match against Werder Bremen in the afternoon.
Dortmund were humiliated 5-1 at home by Stuttgart on Saturday and slipped to fifth place, out of European positions.