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Breakthrough in Cancer Research? Known drug can cause tumor cells to die


Cancer research is making progress. Now a diarrhea drug is showing promising study results. It can kill tumor cells.

Cancer research is making progress.

Now a diarrhea drug is showing promising study results.

It can kill tumor cells.

  • Brain tumors

    often lead to



    cancer patients


  • Now researchers are celebrating a

    new finding


  • A diarrhea drug

    kills tumor cells


Kassel - The risk of



cancer has

continued to decline within the European Union in recent years - if you take the age structure of the population into account, scientists write in the specialist magazine "Annals of Oncology".

Scientists are now celebrating a

supposed breakthrough in cancer therapy


The reason: A diarrhea drug is delivering promising study results.

The most common types of cancer are:

  • Breast cancer

  • Prostate cancer

  • Colon cancer

  • Lung cancer

  • Skin cancer

  • cervical cancer

  • Pancreatic cancer

Brain tumors often lead to the death of cancer patients

So far,

brain tumors in the form of a so-called


can only be treated to a very limited extent.

They often lead

to the death of the cancer patient


However, these brain tumors react to


, as researchers have now found out in a recent study, reports

"In cell culture, the common anti-diarrheal agent, loperamide, works against glioblastoma cells," says a message from Goethe University in Frankfurt. 

In cell culture, the anti-diarrheal agent loperamide acts against glioblastoma cells.

A research team from the Goethe University has now clarified the mechanism of action of the agent & shown how the agent could support the treatment of brain tumors.

More ➡️

- Goethe University (@goetheuni) December 21, 2020

A study by the research team of Dr.

Sjoerd van Wijk from the Institute for Experimental Tumor Research in Pediatrics at Goethe University Frankfurt is now delivering the first results.

Cancer research: Loperamide leads to stress reactions in tumor cells

Accordingly, loperamide causes

stress reactions

in certain tumor cells in the so-called endoplasmic reticulum (ER).

It is a cell organelle.

It is responsible for various steps in protein synthesis, it said.

The stress that is triggered causes the

cancer cells to die


Scientists refer to the process of death as



It is an automatic mechanism to "recycle" cells.

The mechanism separates damaged and superfluous cells from "still good" cell parts.

The body recycles the good and lets the bad



Cancer tumors are not destroyed by simply taking loperamide

With the use of loperamide, so much is

broken down

in certain tumor cells during


that the entire cells die.

There is nothing left in the process for the cells to survive.

This is the case with

brain tumors

in the form of a glioblastoma.


cancer tumors


not simply destroyed

by simply taking



"This autophagy is harmless in normal cells - also for use as a diarrhea remedy, because loperamide only works at special binding sites in the intestine and is not really absorbed by intestinal cells," explains Dr.

van Wijk.

Scientists celebrate success in cancer research

Nevertheless: The fact that loperamide could be used against brain tumors is a very important finding in

cancer research


In addition, doctors could possibly use the drug against

other cancers

and against




can have the following side effects:

  • a headache

  • dizziness

  • constipation

  • nausea

  • Flatulence

  • sleepiness

  • stomach pain

  • Dry mouth

  • Vomit

  • Indigestion

  • Rashes

Only recently had researchers discovered a connection between cancer and corona.

(Jan Wendt)

Source: merkur

All life articles on 2021-01-06

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