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Will this mutation cause re-infections in the corona?
Having shown that the British mutation is not resistant to the vaccine, now the main concern is from the South African mutation which seems a bit more stubborn and dangerous.
So what do we know now that we did not know a week ago?
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Thursday, 21 January 2021, 10:41
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There are growing speculations that the South African version of SARS-CoV-2 may partially slip away from our immune system, indicating that people are not really protected against re-infection if they have previously had COVID-19.
And perhaps even if vaccinated.
The whole question of re-infection with COVID-19, when a person is infected with the disease a second time, is not fully understood, although the accepted assessment is that most people have some protection against re-infection because their immune system has developed antibodies to the virus.
Recent studies from the UK indicate that past infection provides 83 per cent protection for five months.
However, this may not necessarily be true of the South African version, known as 501Y.V2.
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Data show: The South African strain is twice as contagious
To the full article
The National Institute of Infectious Diseases in South Africa has collected a plasma of 44 recoveries from COVID-19.
They were then exposed to the South African version.
Just under half of them did not respond to the mutation with neutralizing antibodies.
The study, which has not yet been peer-reviewed, can be read on the bioRxiv server.
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"Blood samples from half of the people we tested showed that any neutralizing activity was lost. This indicates that they may no longer be protected against re-infection. In the other half, antibody levels were reduced and therefore the risk of re-infection is unknown," the National Infectious Diseases Institute said in a statement. Africa.
The researchers speculate that the South African version evades the antibodies because it involves specific mutations on the prickly protein of the viruses to which the antibodies bind.
What can we expect next?
Corona virus (Photo: Giphy)
Commenting on the findings, Professor Lawrence Young, a virologist and professor of molecular oncology at the Warwick School of Medicine, said: "This is a very thorough study examining the effect of specific mutations in the 501Y.V2 spike gene and how these affect the binding of antibody neutralization."
"The similarity between the 501Y.V2 mutation and the version recently found in Brazil suggests that this Brazilian version will also show significant levels of antibody resistance. This study suggests that people who have been infected in the past may be susceptible to re-infection with mutations of the virus." , Young added.
Professor Young refers to recent reports from Brazil, in which people previously infected with COVID-19 appear to have been re-infected with the South African variable, just as this new study suggests might happen.
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