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Influenza vaccine reduces morbidity in Corona.
why is it happening?
Researchers have found that people who have been vaccinated against the flu are 24 percent less likely to be positive for Covid-19.
Is it a direct biological effect of the vaccine, or something more complex?
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Flu Vaccine
Corona
covid-19
Walla!
health
Wednesday, 24 March 2021, 11:18 Updated: 12:30
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The flu vaccine and the corona vaccine are two different things, but may not be that different.
A new medical study has come to a very interesting conclusion about the effect that a vaccine has on the prevention of morbidity in corona, and the researchers who conducted it do not really know how to explain it.
The study is actually a medical record analysis of more than 27,000 patients in Michigan who underwent corona testing by July 2020. The researchers found that patients vaccinated against influenza in the previous year had a significantly lower chance of being positive for Covid-19, compared to patients who did not receive the vaccine.
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Of the 27,201 people whose data were included in the study, 1,218 were found to be verified for corona (4.5 percent).
This group includes all the verified, both those who were vaccinated against influenza in the previous year and those who were not.
Continuing to delve into the data and segmenting them, a small but significant finding emerges - which concerns the patients' chances of contracting the corona, and remains consistent even after weighting other factors that affect the chances of developing the corona such as: ethnicity, race, gender, age and more.
Those who were vaccinated against the flu and still contracted corona were less likely to get to a hospital.
Influenza vaccines (Photo: Reuven Castro)
The researchers found that of those vaccinated against influenza in the year prior to the study, only 4 percent were found to be positive for corona.
In contrast, among those who were not vaccinated, the chance of infection was 4.9 percent.
Do you feel like a negligible difference?
Try to think of it this way - the researchers calculated the data and found that the chances of those who were vaccinated against influenza being infected with covid-19 were 24 percent lower than those of those who were not vaccinated.
Although the possible protection of the influenza vaccine against Covid-19 seems negligible in relation to the protection afforded to vaccinators in corona vaccines, it still appears from this study that the influenza vaccine can also give the public some protection against the virus.
Now the question arises why does this happen at all?
And the answer is not entirely clear.
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According to the researchers, the source of the effect may not be the vaccine itself, but some kind of behavioral bias, which is more characteristic of those people who have chosen to get vaccinated against the flu: "It is quite possible that people who have chosen to get vaccinated against flu also take additional preventive measures. More on the CDC guidelines for maintaining social distance and the like, "said Dr. Marion Hoffman Bauman, a cardiologist at the University of Michigan. But she added that the possibility that this is a direct biological effect of the flu vaccine on the immune system and that it is relevant to the way Where the body fights the corona virus. "
It is possible that those who take care to get vaccinated against the flu are also more likely to follow the guidelines for preventing infection.
Vaccinated woman (Photo: Reuters)
Whether the explanation is biological or behavioral, it is worth noting that this is not the first retrospective study to suggest that there is a link between other vaccines and some protection against Covid-19 disease.
A number of other studies conducted around the world have found evidence of a similar link, and it seems that the effect of vaccines is broader and touches on more than just the chance of being positive in a corona test.
In the current study in Michigan for example, it was also found that those who were vaccinated against the flu and still contracted corona were less likely to get to a hospital and need hospitalization or respiratory support of respirators.
And other studies show that the flu vaccine also has an effect on mortality.
However, no similar effect on mortality was found in the present study.
The biological explanation
As stated, at this stage it is not possible to determine that the beneficial effect of influenza vaccines stems from a direct biological effect of the vaccine itself, but if it were known to be the cause - what could have been the cause?
One of the researchers' presumed explanations is the existence of an immunological mechanism called "trained immunity," which actually means that exposure to pathogens (in this case, through the attenuated or killed vaccine to the flu) treads the immune system and prepares it to respond to other threats.
"This notion of 'heterologous immunity' may explain the nonspecific responsiveness to other pathogens following one vaccine or another," the researchers from Michigan wrote in their paper, noting that the issue should be further investigated until it can be confirmed that this is indeed the case.
Although we do not yet know why this effect of influenza vaccines occurs on the chances of infection with Covid-19, there is no doubt that this is another benefit to the right of influenza vaccines.
"Even if the direct link between flu vaccines and disease prevention in Corona is minimal," the researchers concluded, "they can still help reduce overall morbidity and especially reduce the number of patients in need of hospitalization and thus alleviate the burden on hospitals."
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