Is corona linked to Alzheimer's disease? - Walla! health

2021-06-19T01:18:41.025Z

The corona is not over yet, and if evidence is needed, it is enough to take a look at a new study that was published recently and revealed a disturbing link between the virus and a degenerative brain disease such as Alzheimer's. Here are the details >>>

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Is corona linked to Alzheimer's disease?

The corona is not over yet, and if evidence is needed, it is enough to take a look at a new study that was published recently and revealed a disturbing link between the virus and degenerative brain disease that causes dementia.

That's what we know

Abolishing the obligation to wear masks raises one very sucking question

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The study authors conclude that there is relatively little evidence to support the theory that COVID-19 targets and attacks the brain directly.

However, close links have been observed between the disease and a number of genes and proteins that have long been linked to a number of neurological diseases, including Alzheimer’s.

Overall, these findings suggest that there are indeed pathways in which COVID-19 "can lead to Alzheimer's-like dementia."

In addition, researchers whose study was published in the journal Alzheimer's Research and Therapy looked for potential links linking the corona to neurological inflammation or damage to the vascular system in the brain - two conditions that are considered warning signs of Alzheimer's development.

Infects brain cells directly?

Gif of the brain (Photo: Giphy)

"While some studies suggest that SARS-CoV-2 infects brain cells directly, other studies have found no evidence of a virus in the brain," says lead research author Dr. Faiyong Chang, an assistant on the Cleveland Clinic's Institute of Genomics. “Identifying how COVID-19 and neurological problems are related will be critical to developing effective prevention and treatment strategies to address the trend of neurocognitive impairments that we expect to see in the near future.

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"We found that SARS-CoV-2 infection significantly altered the Alzheimer's markers involved in encephalitis and that certain viral entry factors are highly expressed in cells in the blood-brain barrier," he continues.

"These findings suggest that the virus may affect some genes or pathways involved in neurological inflammation and microvascular damage to the brain, which may lead to cognitive impairment - like Alzheimer's disease."

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The researchers analyzed data sets from patients with COVID-19 and Alzheimer's disease.

Using artificial intelligence they measured the distance between SARS-CoV-2 host genes and those associated with various neurological diseases when closer proximity offers related or shared disease pathways.

The team also tested genetic factors that allow the SARS-CoV-2 virus to infect brain and tissue cells.

The study findings showed that there is a close network link between SARS-CoV-2 and genes and proteins associated with some neurological disease such as Alzheimer's.

It may cause COVID-19 to cause Alzheimer's-like dementia.

Additional findings showed that those with the APOE E4 / E4 allele received reduced expression of antiviral protection genes, which may explain why some people are more susceptible to the disease.