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Breast cancer: a drug prolongs survival by more than four years and delays the need for chemotherapy

2021-08-02T12:20:51.124Z


The drug reduces the relative risk of death by 36%. The results were presented at the American Congress of Clinical Oncology.


08/02/2021 9:00

  • Clarín.com

  • Society

Updated 08/02/2021 9:00 AM

The

breast cancer

figures are

worrying.

As estimated by the National Cancer Institute, about

21,500 new cases

are diagnosed

per year.

That is,

sixty cases a day.

Specialists emphasize the importance of self-examinations and regular checks.

Every scientific advance in this area is fundamental

, since it has concrete repercussions on the lives of tens of thousands of women. This year, at the

annual Congress of the American Society of Clinical Oncology

-the largest scientific event of the specialty in the world-, very auspicious research was presented for patients in advanced stages of the disease.

It is a clinical study that combines the

drug

ribociclib

together with hormonal therapy

(

fulvestrant

).

Ribociclib

is the only medication of its kind. It had already shown a prolongation of survival in women with a common subtype of metastatic breast cancer, known as RH + / HER2. It is now known that the results are sustained over time.

Based on the new conclusions of the "Monaleesa-3" study, it was observed that

ribociclib

reduces the relative risk of death by 36%

and delays

the progression of the disease by

more than four years

, providing survival to patients.

It also manages to

extend the need for chemotherapy up to four years, compared

to 2.4 years in those who received only hormonal therapy.

The disease progresses to a metastatic stage in one third of women.

"Postmenopausal women generally respond less to therapies when their disease is in

advanced or metastatic stage,

but this medication has shown extremely encouraging results in this group. From the first data we knew that it was able to prolong survival, but now we know that this benefit it continues to be sustained for unthinkable periods a short time ago, "said

 Valeria Cáceres

, clinical oncologist, head of the Clinical Oncology Unit of the Ángel Roffo Institute.

"Some women are initially diagnosed at an advanced stage and that is something we have to avoid, with better awareness strategies about breast controls. In any case, other times they are patients who come with an extensive history of the disease, different treatments, surgeries and one or more relapses. Delaying the need for chemotherapy is very valuable, because all this time gained from a good quality of life in this advanced stage perhaps allows them to remain active and perform daily tasks ", added

 Guillermo Lerzo

, clinical oncologist , Head of the Clinical Oncology Unit of the María Curie Oncology Hospital

.

In the same vein, Cáceres said that a real break is taking place in terms of

new therapies

for the treatment of breast cancer.

One in eight women who live to age 80 will develop breast cancer.

"This gives patients the

possibility of being able to

access new developments in the future

that complement the current approach and continue to contribute to 'chronifying' this oncological disease, when until a few years ago the advanced stages offered few treatment alternatives ", concluded the specialist.

MG

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Source: clarin

All life articles on 2021-08-02

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