Messi and Neymar will start from the bench in the PSG challenge with freshman Clermont, third.
Pochettino will field Mbappé-Icardi-Draxler, the 'Pulce' should still make its debut in the Parco dei Principi just after beating Pele's record among South American goalscorers.
The most awaited challenge is Monaco-Marseille, while Lyon and Lille try to redeem themselves, facing Strasbourg and Lorient.
Check for Angers, according to surprise, in the home of Brest.
The picture of the fifth day
Lorient-Lille at 9pm
Paris SG-Clermont Saturday at 5pm
Monaco-Marseille at 21
Montpellier-St.
Etienne Sunday at 1pm
Bordeaux-Lens 3 pm
Brest-Angers
Metz-Troyes
Rennes-Reims
Nantes-Nice at 17
Lyon-Strasbourg 8.45 pm