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335 days: A woman has been positive for Corona for nearly a year

A woman from the US is the longest documented case of continuous infection with the corona virus, after doctors discovered that she continued to carry the active virus in her body even 11 months after she first became ill. How did this happen and what can be learned from it?

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• Corona

• covid-19

• Corona virus

• Corona test

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Sunday, 24 October 2021, 10:15 Updated: 10:20

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In the video: Research on the corona vaccine in 18-12 year olds: 90% effectiveness in infection and 93% in preventing symptoms (Photo: Clalit Health Services)

A woman who has recovered from cancer holds a new world record as someone who has been positive for the corona virus for the longest time.

A new study has found that the woman carried the virus in her body for 335 days, which is about 11 months.

Details of this exceptional case were published on the online pre-print platform MedRxiv where peer-review articles are published, before they go down in print in one of the scientific journals.

The unnamed 47-year-old woman was first hospitalized with Covid-19 at the Bethesda Maryland National Institutes of Health Hospital in the spring of 2020. 10 months after being released from the hospital, her doctors were shocked to discover she was still positive for Corona in tests performed on her.

During the post-discharge period, the woman who experienced mild symptoms of the disease recounted and later those also subsided.

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In an article describing her unique case, doctors explained that the woman was at risk for immunosuppressants, after (successful) treatments for leukemia she underwent about three years ago left her with low levels of B cells (one of the cells responsible for producing antibodies in the immune system).

Genetic sequencing has proven - this is the same virus she contracted almost a year earlier.

A lab worker in Rhode Island holds a corona sample (Photo: AP)

Initially, when she continued to come out positive in the PCR tests performed on her, her doctors estimated that these were false positive results, resulting from the identification of harmless virus particles that are still present in her body following her initial infection.

However, when a test performed on her in March 2021 signaled a resurgence of the viral load on her body, the doctors decided to perform a genetic sequencing of the virus sample taken from her, to understand what exactly was going on here.

But the results of the flooring only confused them more: the virus that circulated in her body was almost identical to the same virus that had infiltrated her body in the initial infection 10 months earlier.

In addition, no genetic match was found between him and any of the common species circulating in the general population at that time.

So their conclusion was that it was the same original infection that was still active in the woman's body.

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  It's the truth

Passes dozens of mutations within the immunocompromised body.

Corona virus (Photo: ShutterStock)

The woman received drug treatment against the virus and in April 2021 - 335 days after she was first infected with it - she finally got a negative result on a PCR test.

And not one, but a number of tests performed on her, because both she and her doctors wanted to make sure this time it was really over.

Documenting the case of this woman and other similar cases, help doctors better understand how covid-19 affects people with weakened immune systems.

People with immunosuppression are less likely to develop adequate immune protection, even after being vaccinated.

And even after vaccination they remain more vulnerable to virus infections.

Monitoring particularly long cases of infection allows doctors and scientists to better understand what happens to the virus when it is in an environment with low immune protection.

For example, in the case of a woman who was HIV-positive and found to be positive for corona for 216 days, doctors monitored the virus and found that it had undergone at least 30 mutations during the time it was inside its body.

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