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Disturbing: The link between depression at age 20 and dementia at age 80 - Walla! health

2021-10-26T07:08:44.988Z


Dementia has become a much more common disease than in the past, mainly due to the aging of the population. New research sheds light on a particularly troubling link between the disease and depression at a young age


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Disturbing: The link between depression at age 20 and dementia at age 80

Dementia has become a much more common disease than in the past, mainly due to the aging of the population.

In addition, no effective cure has been found for it, so many researchers are examining it from all directions and looking for its source.

New research sheds light on a particularly troubling link between the disease and depression at a young age

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  • dementia

  • depression

Walla!

health

Tuesday, 26 October 2021, 09:31 Updated: 09:56

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Five things you may not have known about the brain ("not to be missed" system)

Does your mental health in your 20s determine the risk of dementia decades later?

New research reveals that happiness in your 20s may be the best medicine for your brain in old age.

Researchers at the University of California, San Francisco have found an association between depression at younger ages and cognitive decline as these people reach older age.



The study, published in the Journal of Alzheimer's Disease, adds to the body evidence linking depression to dementia, but while most studies have pointed to its association with later life, this study shows that depression at an early age may lead to cognitive decline 10 years later and cognitive decline in older people.

More on Walla!

The frightening effect your negative thoughts have on the brain

To the full article

The researchers used a statistical model to predict the pathway of depressive symptoms among a group of 15,000 participants aged 20 to 89 years.

The study authors divided the group into three categories: young adults, middle-aged people, and the elderly.

Depression of age 20 can lead to dementia of age 80. Gif of a depressed man (Photo: Giphy)

Those who experience depression, stress and anxiety often also contribute to their poor mental health.

The authors of the study claim that it also causes the brain to be able to properly store and preserve memories, a common side effect of dementia.

"Several mechanisms explain how depression may increase the risk of dementia," says author Villa Baranovich, a doctoral student in the Department of Behavioral Psychiatry at the University of San Francisco and the Will Institute of Neuroscience.

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"One of these mechanisms is the hyperactivity of the central stress response system that increases the production of stress hormones glucocorticoids, leading to damage to the hippocampus, the part of the brain essential for creating, organizing and storing new memories."



Previous studies have also found an association between crumbling hippocampus and depression, with one study showing that women suffer from brain volume loss faster than men.

The risk of depression only increases as we get older

The authors of the study used a questionnaire that included 10 questions to assess the level of depression of each participant in the past week.

The team found moderate to high depressive symptoms in 13 percent of young adults, 26 percent of middle-aged adults and 34 percent of adults.

Nearly 1,300 participants were also diagnosed with cognitive impairment after performing a neuropsychological examination.



"In general, we found that the greater the symptoms of depression, the lower the cognition and the faster its rate of decline," Baranovich adds.

"For adults assessed as having moderate or high depressive symptoms in early adulthood, a decrease in cognition of over 10 years was found."

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Source: walla

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