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Researchers have compared the efficacy of 9 corona vaccines. This is what they discovered - Walla! health

2021-12-08T06:47:11.297Z


The Hebrew University rated all vaccines against Corona, and found that Pfizer vaccines are 85 percent less likely to get Corona compared to vaccines from other companies.


Researchers have compared the efficacy of 9 corona vaccines.

This is what they discovered

The Hebrew University rated all vaccines against Corona, and found that Pfizer vaccines were 85 percent less likely to get Corona compared to vaccines from some other companies.

Here are all the details

Walla!

health

08/12/2021

Wednesday, 08 December 2021, 08:04 Updated: 08:37

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In recent days everyone has been worried about the effectiveness of vaccines against the corona ominone strain, but what we sometimes forget is that not all vaccines are equally effective.

There are corona vaccines that give higher protection, and some that are less so.

Now a new study by the Hebrew University has examined all existing vaccines against corona, and found who is the most effective.

The researchers found that Pfizer vaccines are 85 percent less likely to get corona compared to Astraznica and Johnson vaccines.

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To the full article

The researchers, from the School of Pharmacy and the Faculty of Medicine at the Hebrew University of Jerusalem, compared the efficacy of nine vaccines against symptomatic coronary heart disease and severe disease in the adult population.

In the study, published in the journal Scientific Reports from the Nature Group, the researchers compared the effectiveness of new vaccines against corona, based on the results of clinical trials conducted on each vaccine individually.



The method of analysis used is called network meta-analysis (NMA) - a method that allows to compile and compare results from different studies, even when in none of the studies was a direct efficacy test of one vaccine compared to another.

The use of data analysis makes it possible to evaluate the relative efficacy between each pair of vaccines and even rate them in terms of the probability of being the most effective vaccine.

A clear advantage for Pfizer and Moderna.

A person gets vaccinated at the Corona vaccine compound (Photo: Reuven Castro)

The vaccines included in the study are: two mRNA vaccines - from Pfizer and Modern;

Two vaccines that use a different virus (adenovirus) that carry a DNA fragment of the corona virus - a vaccine from the Astraznica company and a Sputnik vaccine;

Vaccine that uses adenovirus to transmit Johnson's Corona virus S protein;

A vaccine containing Novavax corona virus S protein;

Three vaccines based on "classic" technology containing inactive corona virus from Sinopharm and Sinovac.

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The researchers rated the probability that a particular vaccine would protect better compared to all other vaccines, and these were the results obtained:



• Pfizer - 95 percent


• Modern - 84 percent


• Sputnik - 78 percent


• Novavax - 70 percent


• Sinovac - 57 percent


• Two Sinopharm vaccines - 43 And 33 percent


• Johnson and Astraznica - 20 percent

MRNA vaccines are more effective

According to the results of the study, the subjects vaccinated with mRNA vaccines, from Pfizer and Moderna, have the lowest relative risk of developing symptomatic corona, compared to the other recipients of the vaccines tested in the data analysis.

As mentioned, Pfizer vaccinated had a 85 percent lower risk of developing symptomatic disease compared with Astraznica and Johnson vaccinated.

A similar figure (79 percent) was observed among modern vaccines compared to Astraznica and Johnson.

Two mRNA vaccines were rated as having the highest probability of preventing symptomatic disease in the adult population compared to other vaccines.



In addition, a trend of higher efficacy of mRNA vaccines in the prevention of severe coronary heart disease has been observed.

The researchers found no difference between the different vaccines in terms of their effectiveness in preventing symptomatic disease in a population over the age of 65.

MRNA vaccines are also more effective in preventing severe coronary heart disease.

Medical worker prepares corona vaccine (Photo: AP)

The results of the study can contribute in determining the vaccination policy in combination with other variables such as the availability of the various vaccines, side effects, costs, storage conditions, transportation and more.

However, the researchers qualify the results and note that the NMA method combines the results of different studies, assuming that the studies are similar in terms of design, population, when in practice there are always differences to one degree or another between the studies.



This is especially important in the context of corona studies, where we are witnessing varying waves of morbidity in terms of population morbidity level, geographical location, different variants of the virus and their resistance to vaccines.

Each variable may affect the results of vaccine efficacy in each study individually and thus affect relative efficacy.

  • health

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Tags

  • Vaccine for corona

  • Corona

  • Pfizer

  • Modern

  • Johnson

Source: walla

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