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Antibody titer increased 23-fold: Which corona vaccination develops particularly good omicron protection

2022-04-07T03:11:01.096Z


Antibody titer increased 23-fold: Which corona vaccination develops particularly good omicron protection Created: 2022-04-07 04:51 By: Juliane Gutmann A corona vaccination protects against severe disease progression or prevents the disease from breaking out in the first place. But does this also apply to Omikron? It feels like everyone is currently infected with Omikron. According to the curre


Antibody titer increased 23-fold: Which corona vaccination develops particularly good omicron protection

Created: 2022-04-07 04:51

By: Juliane Gutmann

A corona vaccination protects against severe disease progression or prevents the disease from breaking out in the first place.

But does this also apply to Omikron?

It feels like everyone is currently infected with Omikron.

According to the current state of knowledge, the corona variant results in less severe disease progression*, but is far more contagious than the Delta virus mutation or the wild type of the virus.

In order to protect yourself from potentially life-threatening courses and Long Covid, health authorities worldwide recommend the corona vaccination.

In Europe, the vaccines from the manufacturers Biontech and Pfizer, Moderna, AstraZeneca, Janssen Pharmaceutica NV and Novavax are available.

As the European Commission has informed, conditional approval was granted in the five cases after the European Medicines Agency (EMA) had positively assessed their respective safety and effectiveness.

But the omicron variant poses new challenges for vaccine manufacturers.

Because if a virus changes significantly, the vaccine has to be adapted again and again.

This is currently happening in the manufacturers' laboratories.

Biontech, developer of the corona vaccine Comirnaty, informs in a study published in the journal Science: "In people who received only two doses (Comirnaty), the ability to neutralize the omicron variant was low, while one third dose of BNT162b2 markedly improved omicron recognition by antibodies”.

One month after the third dose of vaccine, omicron-neutralizing antibody titers were 23-fold higher than levels after two doses.

Survey on the course of corona disease

Antibodies against omicron: Only the booster protects

The Medical University of Vienna has also addressed the question of how well currently used vaccines work against omicron.

The sobering result of the Austrian researchers:

There is practically no protection against an omicron infection for people who have been vaccinated twice and who have recovered from previous SARS-CoV-2 variants such as Delta

.

The press release from the Medical University of Vienna also says: "Only people who have been immunized against COVID-19 with a third corona vaccination form antibodies that Omikron can also partially block".

Does the corona vaccination work against omicron?

© Stefan Puchner/dpa

Study leader Rudolf Valenta from MedUni Vienna's Institute of Pathophysiology and Allergy Research and his team had investigated how vaccinations affect the body's own protection against delta, omicron and the corona wild types.

"

The third vaccination has developed sufficient antibodies in many people to protect them from omicron infection,

" explains Valenta, according to the press release.

"However, there is also a significant proportion here, at 20 percent, where no protection has been established".

The immunologist advocates the development of a broadly effective combination vaccine that protects against all variants: "

Until we have such a vaccine, only repeated vaccinations with the existing vaccines offer protection

," says Valenta.

(jg) *Merkur.de is an offer from IPPEN.MEDIA.

Source: merkur

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