Mississippi governor Tate Reeves declared a health emergency after a historic flood damaged the sewage system leaving the capital's 180,000 residents without clean water.
Reeves also sent the National Guard to the city for water distribution.
Authorities have warned against drinking tap water because it is contaminated or untreated.
But the city is also without water to fight any fires or simply to ensure the flow of the toilet flush in the toilets.
The US government is ready to provide support to Mississippi
as soon as it gets an official request from that state, White House spokeswoman Karine Jena-Pierre said, assuring that the administration will continue to work with the state of Mississippi to help communities. affected by the floods.