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Photo: Marcel Kusch/ picture alliance/dpa
A coach with around 60 school children from Belgium drove into a traffic safety trailer in Middle Franconia.
According to the police, there were several minor injuries.
The accident happened around 2.30 a.m. in the construction site area between the Höchstadt Nord and Schlüsselfeld junctions.
More than 50 volunteer firefighters and 25 emergency services were deployed.
Autobahn 3 was completely closed in both directions after the accident early on Wednesday morning.
Five children injured
The driver of the bus was taken to a hospital with minor injuries.
The rescue service treated five slightly injured children on site, the other occupants were unharmed, according to the police.
The bus was on the way back from a school trip when it drove into the parked traffic safety trailer on the A3 towards Würzburg in the construction site area.
After the accident, the children found shelter in a nearby sports hall.
It was initially unclear how the accident happened.
ala/dpa