Arsenal won 1-0 at Leicester and continue their solitary run at the top, while City are awaited by Bournemouth.
The most disheartening fact for the Premier is that, apart from Man City, the other big names risk marking time in the Champions League, given the nonetheless remediable defeats of Chelsea and Tottenham, and the collapse of Liverpool.
And the two Londoners face each other on Sunday in the big match, a very delicate derby.
Tottenham are still fourth and Conte shouldn't be on the bench due to the after-effects of the gallbladder operation, while Chelsea are sinking into an endless crisis despite the millionaire signings.
The blues are -11 from the fourth place of the Gunners and a further knockout could put Potter in trouble.
Klopp is also in bad shape because Liverpool seem to be at the end of the cycle with so many champions in decline,
but the away match with Crystal Palace could represent a new relaunch.
Manchester United, who knocked out Barcelona in the Europa League play-offs, are favorites in the League Cup final contending with surprise of the season Newcastle.
Overview of the 25th day (RESULTS AND STANDINGS)
Fulham-Wolves 1-1
Newcastle-Brighton postponed
Everton-Aston Villa 0-2
Leeds-Southampton 1-0
Leicester-Arsenal 0-1
West Ham-Nottingham 4-0
Bournemouth-Manchester City 18.30
Crystal Palace-Liverpool 20.45
Manchester Utd -Brentford postponed
Tottenham-Chelsea on Sunday at 14.30