Two US research teams have now found out in studies that the current epidemics in Europe and North America were only triggered at the second attempt.
After the outbreak of the
coronavirus pandemic *
, this topic is
being researched
worldwide
*
.
Studies by
two US research teams now show that the current epidemics in
Europe
and
North America were
only triggered at the second attempt.
We have
summarized
basic
facts about the coronavirus *
for you
.
We also offer you the current number of cases in
Germany
as well as the Corona news from Germany
on a map
.
Munich / Tucson / Seattle - In order to find out how the
coronavirus
could spread
in
Europe
and
North America
, two US research
teams
examined different virus lines of
SARS-CoV-2
and what role the first
infected people
played.
They found out that the current epidemics were only triggered at the second attempt.
The two studies, which were published in the journal
Science
, show that the first infections in
Bavaria
and in the
US state of Washington could
still be warded off.
Corona: Initially speculation about the “cryptic epidemic
On
January 19
was in
Seattle
in the
state Washington US
the first
Corona infection
in a person in
North America
found that four days earlier from
China
had entered.
The actual
epidemic
did not begin until the
end of February
, six weeks later.
It was similar in
Europe
.
The first infection was detected
in
Bavaria
on
January 28
, before
the corona outbreak began in
northern Italy
around
February 20
.
Initially, it was assumed that the first two outbreaks could not be controlled and that the
coronavirus
triggered
a
"cryptic" epidemic
that was not noticed by the health authorities, as the German Medical Journal reports.
In the previous hypothesis, the virus is said to have spread from
Bavaria
to
northern Italy
and from there
returned to
Germany
via
Ischgl
.
Similarities in the
virus sequence supported
this assumption.
Coronavirus: The results of the studies speak against the "cryptic" epidemic
A
genome comparison
of
455 SARS-CoV-2 isolates
that
Trevor Bedford
from the
Fred Hutchinson Cancer Research Center
in Seattle and his team carried out initially also seemed to confirm this.
However, a more detailed analysis showed that the virus probably didn't arrive until
February 2nd
.
This date can be calculated from the assumption of a mutation rate and the differences in the genome sequences of the viruses that were later isolated, the Ärzteblatt continues.
# SARSCoV2 circulated undetected for several weeks in Washington State, suggests a genomic study by @trvrb et al.
The study's review of @seattleflustudy data also found evidence of # SARSCoV2 before the first previously reported community case in the state.
https://t.co/q36DqDSL1G pic.twitter.com/YoNyzcpPRc
- Science Magazine (@ScienceMagazine) September 10, 2020
An analysis of the
“Seattle Flu Study” also
speaks against a
“cryptic” epidemic
after the first infection.
Between January 1 and March 15, a total of
10,382 airway swabs were
taken.
The
first positive test
was found on
February 21
, more than a month after the first
corona infection
in
North America
.
After this point in time, a further
5,112 samples were
taken by
March 15,
65 of
which were
positive for
SARS-CoV-2
.
The dynamics after February
21
are difficult to reconcile with an earlier arrival of the virus, explains the German medical journal.
Corona study: Worobey and Co. simulate different spread scenarios
Michael Worobey
from the
University of Arizona
at
Tucson
and his colleagues come to a similar conclusion in their study.
Based
on the first cases in Europe and North America, the researchers simulated various
spread
scenarios
for the
coronavirus
and then compared the results with the
virus genomes
and
epidemiological data
obtained on site
.
“This enabled us to compare the scenarios determined in the simulations with the patterns that we saw in reality,” explains
Worobey
.
The first two cases do not fit into the picture of the later eruptions.
Early
containment
measures initially prevented further transmission of the
coronavirus
.
The researchers report: "Only later introductions of the virus from China to Italy and Washington then established the first infection networks in Europe and the USA." The first
infection
in
Bavaria
caused a short chain of infection, but this was possible through quick
isolation
and
tracking
being stopped.
The
gene signature of
this
SARS-CoV-2
variant did not appear in later cases.
Coronavirus study: outbreak in northern Italy through direct introduction from China
With their analysis, the researchers were also able to pinpoint the source of the first major European outbreak in
northern Italy
.
According to the
genetic data
, not a single virus in the Italian outbreak is identical to the Bavarian strain,
Worobey
and his team
explain
.
All
coronavirus samples
isolated
in
northern Italy
from the
beginning of February
differ in at least one mutation from the Bavarian infection cluster.
"Our data and simulations support the scenario of an independent introduction of the virus from China first to Germany and then to Italy," the researchers explain.
According to the study, the
outbreak in
northern Italy
began with a
direct introduction
of
SARS-CoV-2
from
Hubei, China,
around
January 28th
.
From
Italy
, the
corona virus
spread via travelers in
Germany
and other European countries.
Worobey
reports
that this variant of the virus was also introduced to
New York City
around
February 12,
where it triggered the severe outbreak
.
Corona spread on the west coast of the USA is also only in the second attempt
The spread of the
coronavirus
on the
west coast of the United States
was also examined by the researchers.
They came to the conclusion that the virus variant of the first
Covid-19 case
in
Seattle
in the
US state of Washington
on
January 19
could not multiply or
last
.
The infected people tested in the following weeks carried a slightly different variant of the
coronavirus
.
The researchers' simulations also speak against the assumption that the first case was the focus of the following epidemic.
Public health responses to the earliest # SARSCoV2 cases in Washington State & Germany did not lead to major outbreaks, say @uarizona researchers who studied how and when the # SARSCOV2 pandemic unfolded in Europe and North America.
https://t.co/v3VscQrk5m pic.twitter.com/EDqY9mxlPH
- Science Magazine (@ScienceMagazine) September 10, 2020
“We have not been able to simulate a single epidemic scenario that corresponds to the real virus lineages,”
Worobey
and his colleagues
explain
in their study.
They conclude that the first major
Corona outbreak
on the
West Coast of the United States
therefore by one or more re-
introductions
of the virus from
China
to the
February 1, 2020
was caused around.
Corona: Early measures at least delayed the start of the pandemic
The researchers' results show that the early measures in
Seattle
and
Bavaria
at least delayed
the start of the pandemic in
Germany
and the
United States
.
“The early measures meant that the first sparks could still be released successfully.
Even if the epidemic did finally get through, these were early wins that show us how it's done: extensive testing and case tracking are powerful weapons, ”explains
Worobey
.
The first
studies
on the global spread of the
coronavirus were
already carried out in the spring of this year
.
A study by the
Innsbruck University Hospital
illustrates the extent of
corona patients
who had to be treated in hospital.
A Europe-wide
corona study
shows which children are most affected by
Covid-19
.
The
Robert Koch Institute
examined
infection
environments
in a study
.
(ph) * Merkur.de is part of the Ippen-Digital editorial network
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