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Trump positive for Covid-19: what treatments are given to the US president?

2020-10-03T18:17:53.948Z


Synthetic antibodies still experimental to boost the immune system, antiviral used against Ebola but also vitamins. The immu


With "the president's permission," prescriptions for drugs administered to Donald Trump by his personal physician have been made public on Twitter.

We learn that the American head of state was injected with a "single" dose of 8 g - the highest dosage - of an experimental cocktail based on synthetic antibodies manufactured by Regeneron, a biotechnology company of 'across the Atlantic having received $ 600 million from the government to develop this treatment.

He's supposed to run into the virus to neutralize it.

"This must prevent interactions of the virus with cells and therefore block their infection", decrypts immunologist Morgane Bomsel, director of research at the Institut Cochin in Paris.

Only here, this treatment is still in the trial phase, still not approved by the drug gendarme across the Atlantic.

Data on its effects remain limited, although they seem promising.

The first tests on 275 patients would have, in fact, reduced the amount of virus present in infected people and accelerated their recovery.

The press release released on October 2 by Donald Trump's doctor.

/ REUTERS / The White House  

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The Regeneron boss told CNN that he hoped his remedy would "boost the immune system" of the leader of the United States.

According to specialist Morgane Bomsel, there is, in principle, no toxic risk.

"The only danger is that nothing happens," she explains, recalling that "nothing has been demonstrated" for the time being.

She also points out that "the antibodies injected will not stay in the body for long", which could limit the effectiveness of blocking the infection.

"We cannot say that Remdesivir is very effective"

The Republicans billionaire is also on the antiviral Remdesivir designed by an American laboratory initially to treat the Ebola virus.

"It must prevent the replication, the multiplication of the virus", describes Morgane Bomsel.

But it did not give "consistent results in all studies".

“Overall, with a little hindsight, we cannot say that it is very effective,” she summarizes.

In France, according to the evaluation of the High Authority of Health (HAS) made public on September 17, there are "still a lot of uncertainties on the efficacy and tolerance" of Remdesivir.

"The actual benefit is considered low given the current preliminary data which show an overall reduction of four days in the patient's clinical recovery time (eleven days instead of fifteen) compared to placebo, and in addition to support, which is of debatable clinical relevance ”, notes, doubtfully, the HAS.

Finally, the tenant of the White House was prescribed zinc, vitamin D and famotidine intended to "strengthen his immune system" as well as melatonin.

"This removes the virus receptor which, then, cannot enter a cell and therefore infect it", explains the expert.

No hydroxychloroquine, however.

The malaria drug dear to Marseille professor Didier Raoult had yet been acclaimed by the American head of state who had even swallowed it as a preventive measure in May with a great deal of communication.

Source: leparis

All news articles on 2020-10-03

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