A German company and its US partner have come much closer to a corona vaccine.
So will we soon have the pandemic under control?
It's not that easy.
The way to a
corona vaccine
is apparently not far.
A German-American study by
Pfizer
and
Biontech
achieved a
breakthrough
.
But it is still too early for hasty euphoria.
New York / Mainz - It was the news that many people all over the world have been eagerly waiting for.
In the race for a possible
vaccine
*
against the
coronavirus
*
, the pharmaceutical manufacturer Pfizer has achieved a
breakthrough
.
Together with its German partners from
Biontech, the
US company has
developed
a
means
that could soon be used in the fight against the
corona pandemic
.
As both companies announced on Monday, the first
interim results
from the phase III testing processes of the
vaccine candidate give
hope.
Corona vaccine: According to interim results, Biontech-Mittel offers 90 percent protection
According to initial findings, the agent should
offer
around 90 percent vaccination protection
against
COVID-19
disease
.
The ongoing study of the potential vaccine is being monitored by the Data Monitoring Committee (DMC), an independent group of experts.
The experts found
"no serious safety concerns"
.
Pfizer and Biontech, headed by company founder Ugur Sahin, are therefore likely to approach the
American FDA
in order
to apply for
approval of
the vaccine.
Hope made in #RLP.
đ·đŹđ©đȘđșđž # Biontech from #Mainz and #Pfizer want to apply for approval for # Corona # vaccine.
Study data showed that it offers around 90 percent protection against # COVID19.
pic.twitter.com/dhOqKJRdjJ
- State government of Rhineland-Palatinate (@rlpNews) November 9, 2020
Corona vaccine: Still some question marks behind Biontech and Pfizer funds
But can the new "wonder drug"
BNT162b2
really
bring about
a quick return to normal everyday life?
It's not that simple, some questions still remain open.
On the one hand, according to Leif-Erik Sander, head of the Infection Immunology and Vaccine Research research group at the Charité in Berlin, it still needs to be clarified whether the supposed corona vaccine
can be as
effective
as in the study in
high-
risk patients
.
The Charité employee also cannot conclusively see
how long the corona vaccination protection will last
and whether the vaccinated can actually be administered the drug
safely
.
Sander: âAccording to the company, there are no safety-relevant side effects.
However, it must be pointed out that the
observation period for relevant vaccine side effects is still too short
. "
Another point of criticism from the experts' point of
view was
the
selection of study participants
by Pfizer and Biontech.
Some of them were bothered by the fact that
corona-infected people
*
with
rather mild symptoms
were counted as cases.
So it is very difficult to classify whether the vaccine is able
to prevent
infections with very severe courses
or
whether
it can completely prevent infections without symptoms.
Corona vaccine: Biontech admits possible "fluctuations"
There is
also an additional question mark
behind the
interim results
.
In scientific studies on possible vaccines, it is known that the
factor of chance has
a greater influence in efficacy studies, the lower the number of infected people among the study participants.
Thus, in the
event of premature approval
, the
effectiveness
could
prove to be a fallacy in retrospect.
Biontech also raised concerns: "While the study is still ongoing, there may be
fluctuations in the value for vaccine
effectiveness."
In the current
Pfizer / Biontech study
, as is usual in such cases,
one group of subjects received placebos
and the
other group received the vaccine
.
In total, the companies confirmed 94 corona cases.
With 90 percent effectiveness, 86 of the cases must have occurred in the placebo group, only eight in the vaccinated.
Dear World.
We have a vaccine!
Best news since January 10. https://t.co/KtQCHcCc3Y
- Florian Krammer (@florian_krammer) November 9, 2020
In order to successfully complete the vaccine study, the German-American cooperation must be
able to prove
a total of
164 corona cases * among the test
persons.
Of these,
a maximum of 53
should then
occur
in the vaccinated
, which
would
exceed the
effectiveness value of 50 percent
recommended
by the
World Health Organization (WHO)
for approval
.
So we're
not quite there in
the hunt for a vaccine
.
Nevertheless, virus expert Florian Krammer from the Icahn School of Medicine at Mount Sinai Hospital in the USA is probably correct in his assessment: "To be honest, this is the
best news
I have received
since January 10th
."
(Kh) * Merkur.de is part of the nationwide Ippen digital editorial network
List of rubric lists: © Andreas Arnold / dpa / picture alliance