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Corona vaccine: hope for Biontech funds - but some questions remain open

2020-11-10T16:11:49.400Z


A German company and its US partner have come much closer to a corona vaccine. So will we soon have the pandemic under control? It's not that easy.


A German company and its US partner have come much closer to a corona vaccine.

So will we soon have the pandemic under control?

It's not that easy.

  • The way to a

    corona vaccine

    is apparently not far.

  • A German-American study by

    Pfizer

    and

    Biontech

    achieved a

    breakthrough

    .

  • But it is still too early for hasty euphoria.

New York / Mainz - It was the news that many people all over the world have been eagerly waiting for.

In the race for a possible

vaccine

*

against the

coronavirus

*

, the pharmaceutical manufacturer Pfizer has achieved a

breakthrough

.

Together with its German partners from

Biontech, the

US company has

developed

a

means

that could soon be used in the fight against the

corona pandemic

.

As both companies announced on Monday, the first

interim results

from the phase III testing processes of the

vaccine candidate give

hope.

Corona vaccine: According to interim results, Biontech-Mittel offers 90 percent protection

According to initial findings, the agent should

offer

around 90 percent vaccination protection

against

COVID-19

disease

.

The ongoing study of the potential vaccine is being monitored by the Data Monitoring Committee (DMC), an independent group of experts.

The experts found

"no serious safety concerns"

.

Pfizer and Biontech, headed by company founder Ugur Sahin, are therefore likely to approach the

American FDA

in order

to apply for

approval of

the vaccine.

Hope made in #RLP.

đŸ˜·đŸ”ŹđŸ‡©đŸ‡ȘđŸ‡ș🇾 # Biontech from #Mainz and #Pfizer want to apply for approval for # Corona # vaccine.

Study data showed that it offers around 90 percent protection against # COVID19.

pic.twitter.com/dhOqKJRdjJ

- State government of Rhineland-Palatinate (@rlpNews) November 9, 2020

Corona vaccine: Still some question marks behind Biontech and Pfizer funds

But can the new "wonder drug"

BNT162b2

really

bring about

a quick return to normal everyday life?

It's not that simple, some questions still remain open.

On the one hand, according to Leif-Erik Sander, head of the Infection Immunology and Vaccine Research research group at the Charité in Berlin, it still needs to be clarified whether the supposed corona vaccine

can be as

effective

as in the study in

high-

risk patients

.

The Charité employee also cannot conclusively see

how long the corona vaccination protection will last

and whether the vaccinated can actually be administered the drug

safely

.

Sander: “According to the company, there are no safety-relevant side effects.

However, it must be pointed out that the

observation period for relevant vaccine side effects is still too short

. "

Another point of criticism from the experts' point of

view was

the

selection of study participants

by Pfizer and Biontech.

Some of them were bothered by the fact that

corona-infected people

*

with

rather mild symptoms

were counted as cases.

So it is very difficult to classify whether the vaccine is able

to prevent

infections with very severe courses

or

whether

it can completely prevent infections without symptoms.

Corona vaccine: Biontech admits possible "fluctuations"

There is

also an additional question mark

behind the

interim results

.

In scientific studies on possible vaccines, it is known that the

factor of chance has

a greater influence in efficacy studies, the lower the number of infected people among the study participants.

Thus, in the

event of premature approval

, the

effectiveness

could

prove to be a fallacy in retrospect.

Biontech also raised concerns: "While the study is still ongoing, there may be

fluctuations in the value for vaccine

effectiveness."

In the current

Pfizer / Biontech study

, as is usual in such cases,

one group of subjects received placebos

and the

other group received the vaccine

.

In total, the companies confirmed 94 corona cases.

With 90 percent effectiveness, 86 of the cases must have occurred in the placebo group, only eight in the vaccinated.

Dear World.

We have a vaccine!



Best news since January 10. https://t.co/KtQCHcCc3Y

- Florian Krammer (@florian_krammer) November 9, 2020

In order to successfully complete the vaccine study, the German-American cooperation must be

able to prove

a total of

164 corona cases * among the test

persons.

Of these,

a maximum of 53

should then

occur

in the vaccinated

, which

would

exceed the

effectiveness value of 50 percent

recommended

by the

World Health Organization (WHO)

for approval

.

So we're

not quite there in

the hunt for a vaccine

.

Nevertheless, virus expert Florian Krammer from the Icahn School of Medicine at Mount Sinai Hospital in the USA is probably correct in his assessment: "To be honest, this is the

best news

I have received

since January 10th

."

(Kh) * Merkur.de is part of the nationwide Ippen digital editorial network

List of rubric lists: © Andreas Arnold / dpa / picture alliance

Source: merkur

All news articles on 2020-11-10

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