The Tübingen-based biotech company CureVac has reached another important milestone in the development of a corona vaccine.
Munich - The Tübingen-based biotech company
CureVac
is about to approve a framework contract for the delivery of its
corona vaccine
to the EU.
The
company announced on Monday evening that a corresponding agreement
would be concluded with the
EU Commission
on Tuesday (November 17)
for the delivery of a total of 225 million vaccine doses.
The order also includes the option to deliver an additional 180 million cans, it said.
The vaccine will be delivered as soon as the effectiveness and safety of the Covid-19 vaccine has been proven.
According to the planned agreement,
Brussels will make
a down payment to finance further development of the vaccine, production and market launch.
The company
initially did not provide any information
about the price on Monday evening at the request of
Merkur.de
*.
The agreement is the EU’s fifth framework agreement with a vaccine manufacturer.
Similar to the Mainz biotech company
Biontech
, the vaccine candidate from
CureVac
is also based
on the
mRNA
method.
Components of the coronavirus genetic material are injected into the body.
In the cells they should then stimulate the body's own immune defense.
CureVac CEO Haas: "Working with governments around the world"
CureVac
“draws on 20 years of experience to develop a vaccine against COVID-19 that can help end the COVID-19 pandemic and enable us all to return to an unrestricted life,” said
Franz-Werner Haas
, Chief Executive Officer of
CureVac
according to press release on Monday.
They are “proud that we are making an important contribution to this and that our COVID-19 vaccine can possibly be made available to the citizens of the European Union.” In addition, they are working with “governments and multilateral organizations around the world to create one To ensure the broadest and fairest possible access to our COVID-19 vaccine candidate, ”said Haas.
CureVac has been
researching a corona vaccine at
full
speed since January.
Only at the beginning of November, after evaluating the data from 250 test subjects, the company declared that the interim results were "very promising".
The results from the first clinical phase in the four test centers in
Tübingen
,
Hanover
,
Munich
and
Ghent
had shown “very good tolerability”.
In addition, the test subjects showed "very good formation of binding and neutralizing antibodies as well as signs of activation of T cells".
The results achieved were very similar to the immune response of patients who were infected with the Covid-19 virus, it said.
CureVac expands production capacities
In view of the positive results, the company intends to start the large-scale phase IIb / III this year.
The vaccine will be tested on over 30,000 subjects in Europe and Latin America.
According to the plans,
Curevac will
then submit an application for so-called rolling approval to the European Medicines Agency (EMA) in the first quarter of 2021.
If all goes well, the vaccine could be available in mid-2021, it said.
In order to meet the expected demand, the company is working flat out to expand its production capacities.
Curevac
is
building
a new plant
in Tübingen
.
It is scheduled to start operating in 2022.
The building for it is already in place.
Now the necessary systems are to be installed.
Curevac
wants to
invest
75 million euros
in the production facilities
alone.
In July, the biotech specialist secured a loan from the European Investment Bank to finance it.
In addition, the existing systems are currently "cloned multiple times".
Now the company is increasing its financial strength.
Similar to the corona vaccines from
Moderna
or
Sanofi
, the preparation from
CureVac
should also be able to be
stored at refrigerator temperatures.
This would simplify the logistics considerably.
The vaccine candidate from competitor
Biontech
, on the other hand,
reportedly
requires arctic temperatures of minus 70 degrees for transport and logistics to ensure its effectiveness.
* Merkur.de is part of the nationwide Ippen Digital editorial network.