Astra Zeneca wants to launch a corona vaccine.
Since a lot has gone wrong so far, there is criticism.
In addition to the health risk, Alexander Kekulé also fears another "danger."
In November, some pharmaceutical companies were able to record successes in corona vaccine research.
The company Astra Zeneca also announced the first results - but revealed weaknesses in calculation.
Top virologist Alexander Kekulé strongly criticizes the Swedish-British company for this - and fears unpleasant consequences.
Munich - Germany, Europe and the world are researching a
corona vaccine
.
In the past few weeks, some pharmaceutical companies such as
Moderna
or
Biontech / Pfizer have made their
first breakthroughs in development.
This means that you can see "light at the end of the tunnel", as
Federal Health Minister Jens Spahn
(CDU) explained.
The situation is also being closely followed among virologists.
But there is not only praise, as has now become
clear
in the person of
Alexander Kekulé
.
Corona vaccine: Astra Zeneca in focus - companies criticized for calculation errors
In a guest
post in
“Welt am Sonntag”,
Kekulé
made the importance of a
corona vaccine
clear
at the beginning
: “There was probably hardly any post-war report that was as important as the one that the new vaccines against
Covid-19
apparently worked.” But they do at all companies?
A
few days ago, the
Swedish-British group
Astra Zeneca
raised doubts as to whether their study is as advanced as that of the “two most promising candidates”,
Biontech
and
Pfizer
, who are currently working together in a cooperative
manner
.
Inadvertently, some of the test subjects were given half a dose of the vaccine and then a full dose four weeks later.
To compensate, the people affected then received two doses of the active ingredient.
Later on, however, it turned out that people who were accidentally vaccinated first with half a dose distort the final result.
The people who were vaccinated with half a dose surprisingly showed significantly better results (90 percent effectiveness compared to 62 percent).
+
Alexander Kekulé is omnipresent in pandemic times.
The director of the Institute for Medical Microbiology at Halle University Hospital is one of Germany's top virologists.
© Screenshot Facebook phoenix corona checked
Corona vaccine: fuss around Astra Zeneca - "not to dispel doubts about the study data"
The manufacturer, who had gradually disclosed the discrepancies, defended his product.
Overall, the probability of protection is still 70 percent - and therefore exactly the minimum value set by the WHO.
The companies
Moderna
as well as
Biontech
and
Pfizer
had previously announced 90 to 95 percent effectiveness.
Astra Zeneca
then came under fire.
Even if the errors have now been recognized, according to
Kekulé there were still
open questions.
“With this milkmaid calculation, the doubts about the study data cannot be dispelled”, says the 62 -year-old
and adds: "Why half a dose should protect better than a whole one cannot be scientifically explained." One approach could probably be another sloppiness by the pharmaceutical company: "Since there were different protocols for partial studies in Brazil and Great Britain, it could seem the superior effect of half the dose is also based on a statistical error. "
Corona vaccine: Kekulé fears Astra-Zeneca scandal will be "cannibalized"
So
did
Astra Zenca work
improperly?
In contrast to other companies,
Kekulé
recognizes
clear deficiencies, because "how the alleged effectiveness of 90 percent was calculated cannot be verified because
Astra Zeneca
does not disclose how many vaccinated people were infected compared to the control group." That is half the dose In addition, it was only tested in younger people (no test person was older than 55 years), put the Munich-born, who
conducts research
at the
University of Halle-Wittenberg
, on alert.
It is "quite possible that the risk group of the elderly is only protected to around 60 percent."
Overall, Astra Zeneca's “hide and seek” and the faulty work including “fine calculation” left deep traces.
Top virologist
Kekulé also
fears "the danger that vaccination critics and corona deniers will cannibalize the faux pas for their cause - although everything has gone perfectly with the other two vaccines so far."
Astra Zeneca
could therefore have done the pharmaceutical industry a disservice.
(as)
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