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What strains, how many were infected and how did Pfizer react: Corona mutations in Israel
The Ministry of Health has diagnosed a new strain from California that has strengthened fears of more corona strains arriving in Israel, along with the one that may yet be formed in Israel.
But until the researchers complete the test, the ministry is following with concern the spread of the mutations from Britain and South Africa.
"It's like fire in a field of thorns"
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Corona virus
Corona mutation
Ministry of Health
Vaccine for corona
Pfizer
Meirav Cohen
Tuesday, 26 January 2021, 17:38
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In the video: Corona vaccination campaign in Israel (Photo: Reuters)
The mutations to the corona virus have been gaining the attention of the top health officials in Israel in recent weeks.
Head of Public Health Services, Dr. Sharon Alrai-Pryce, warned that the health system "helpless" in front of the British mutation, and within two hours had already received another message from the office, this time on a new mutation appeared in Israel.
The origin of the species in question is in Los Angeles, California: The Department of Health announced yesterday (Monday) that the person diagnosed infected four more people, all of whom are only adding to the concern index following the rapid rate of infection created by the two previous mutations that have made the rise - the British and South African. after enter the Brazilian, has not been found in the country. to prevent the infiltration into the government decided to prevent the entry of flights from Brazil, so before making a decision includes the closure of Ben-Gurion airport.
Ministry of health can not say what will be the effects of the new species, but they say the entry of additional mutations to Israel can According to them, even in the situation of hermetically closing the sky, there is a fear of the formation of a new strain, made in Israel. A report by the IDF Intelligence Division published on Saturday stated that "there is an increased likelihood of developing a resistant mutation in Israel. ".
The report explained that "the mass vaccination operation that takes place in parallel with an active outbreak in the country, may lead to 'evolutionary pressure' on the virus."
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Pfizer is reassured and says that there is currently no mutation that is resistant to the vaccine.
Corona Testing Laboratory (Photo: Reuven Castro)
However, Pfizer, whose vaccination campaign was based on its shipments, claims that there is currently no mutation resistant to the vaccine.
Furthermore, Pfizer's vaccine has been approved by the US Food and Drug Administration (FDA) with an efficacy of 95%, even though US approval can only be obtained at 60%.
That is, it is likely to be difficult for the variants currently emerging to be resistant to the vaccine.
According to the National Information and Knowledge Center, from the moment a new strain is formed until the moment it manages to penetrate another country it takes three months if the sky is open, and five months if the sky is closed.
The first case of the British mutation was discovered about a month and a half ago.
Since then, according to the Ministry of Health, it has spread, and about 40% of those diagnosed in Corona all over the country are diagnosed with it.
According to the information currently available to researchers, the British strain is 70% -60% more contagious than the original corona strain.
According to the intelligence report, "We no longer stop the spread of the population." Recent research, including Pfizer's experiments demonstrated that the mutation is sensitive to the vaccine, ie can not resist him.
Also, you can see beams is changing gradually - if the past It harmed adults, today it harms children and young people, and researchers point the finger of blame at the British mutation, but according to the BBC, data show there is no evidence that the British mutation is more common in children than other mutations.
More on Walla!
NEWS
The Ministry of Defense warns: Conditions in Israel could lead to the development of a vaccine-resistant mutation
To the full article
But in recent weeks the Ministry of Health has been concerned about a new mutation - the South African, which has currently been diagnosed in 27 people in nine infection chains.
The trait of the South African mutation is more dangerous, capable of causing re-infection and may even be resistant to the Pfizer vaccine.
That is, the South African mutation has a qualitative change, not just a quantitative one like its British counterpart.
Moderna calmed some of the apprehension yesterday, announcing that the vaccine she had developed was effective against the British and South African mutations.
However, Modern has noted that among the new strains the vaccine is less effective against the South African, and it will conduct pre-clinical trials to test the vaccine against it so that more antibodies are formed to stop it and stop more strains from being detected.
The South African and English strains are similar in their rate of infection.
Clalit's vaccination complex, last week (Photo: Reuven Castro)
"We have no verified information on the potential danger of the South African strain," he explains to Walla!
NEWS Prof. Cyril Cohen, Head of the Immunotherapy Laboratory at Bar Ilan University and member of the Advisory Committee for Clinical Trials of Corona Vaccines.
"Viruses are constantly mutating, although corona viruses are usually more genetically stable. To check if there is a new strain, do genetic sequencing and check if there is a variant that takes over the population relative to the original strain."
The South African and English strains are similar in their rate of infection which raises the infection coefficient R to 1.8.
"Once it's easier to get infected then it's like a fire in a field of thorns, it's very difficult to stop it," says Cohen.
"A new study, from a few weeks ago, examined the plasma of recoverers and found that the mutation appears in the South African strain, and can help the virus evade the antibodies, compared to the English strain or the original strain. The study is in progress and we do not know for sure."
He added that "the study hypothesized that recoverers could be infected again, but it is important to say - this is at the laboratory level and not proven at the population level, because it should be remembered that vaccine efficacy does not come only from antibodies. In the immune system there are two things that fight viruses - B cells. "The virus, and T cells, that destroy and kill our sick cells that have been infected with the virus. Even if the antibodies bind less well to the virus, we need to trust the T cells that will kill our virus."
"We may need a new mutation-resistant vaccine."
Prof. Cyril Cohen (Photo: Official Website, Bar Ilan Spokeswoman)
Prof. Cohen claims that we may join in producing a new vaccine.
"If the mutation appears to be resistant to the vaccine, we will probably need a new vaccine that is also resistant to it, as happens every year with the flu vaccine. This means we may have to go through the vaccination round again. The good news is that drug companies can start producing a new vaccine in a few days. Technology already exists in the current vaccine. "
An AMN report has warned that the British strain infects all age groups, including children. Prof. Cohen says that the virus 'ability to infect depends on receptors. "The virus' ability to infect depends on how many receptors there are in our cells, we believe that children have been less infected so far. They have fewer receptors than adults.
"Because the British strain probably binds better to the cell, it doesn't need a lot of receptors to bind, so it can infect children as well."
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