By Berkeley Lovelace Jr. - CNBC
A single dose of the coronavirus vaccines from the Pfizer and BioNTech laboratories and the Moderna pharmaceutical company is 80% effective in preventing coronavirus infection, according to a study by the Centers for Disease Control and Prevention (CDC, performed with immunized healthcare workers.
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The effectiveness of partial immunization was revealed two weeks after the first dose was given, according to the CDC, which
analyzed nearly 4,000 first-line caregivers and workers between Dec. 14 and March 13
.
The results of the analysis were published Monday and the study participants had no history of coronavirus.
However, two doses of any of these vaccines are better than one, according to the study, which found 90% effectiveness two weeks after the second injection.
"These findings indicate that licensed messenger RNA COVID-19 vaccines, also known as mRNA vaccines, are effective in preventing SARS-CoV-2 infection, regardless of symptoms, among adults of working age and making a living. normal, "the agency concluded," the vaccine is recommended for all eligible individuals. "
Unlike the Johnson & Johnson vaccine, which requires a single dose, the Pfizer and BioNTech and Moderna vaccines require two injections three to four weeks apart.
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Paul Offit, a member of the Federal Drug Agency (FDA) Vaccine Advisory Committee, which reviewed both the Pfizer and Moderna vaccines for emergency use authorization, stated that the study of the CDC is "good news."
However, he said he is concerned that people will think that one dose of the vaccines is "good enough" and will not come back for a second injection.
Studies have shown that immunity appears to be "longer lasting" after the second dose
, he said.
A doctor prepares a dose of Moderna's COVID-19 vaccine at a vaccination center in Caserta, Italy, on March 25, 2021.Ivan Romano / Getty Images
"The reason they are two-dose vaccines is that the second doses give you a virus-specific neutralizing antibody titer that is almost 10 times higher than after the first dose," he told CNBC.
"Most importantly, it can detect so-called cellular immunity, called T-cell responses, which generally provide longer lasting immunity," he added.
Questions also remain about highly contagious variants and whether vaccines will protect mild to moderate forms of the disease.
Among the 3,950 study participants, 63% received both recommended doses, and 12% received only one dose.
The infection rate among participants who were vaccinated was 0.04, compared to 1.38 for those who were not vaccinated.
The study was conducted in Phoenix, Tucson, and other areas of Arizona;
Miami Florida;
Duluth, Minnesota;
Portland, Oregon;
Temple, Texas;
and Salt Lake City, Utah.
Most of the participants were female, white, and did not have chronic medical conditions, according to the CDC.
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The effectiveness findings of both vaccines in a normal living environment complement and expand the vaccine effectiveness estimates from other recent studies
, the CDC adds.
A study published in the New England Journal of Medicine in February revealed that Pfizer's vaccine had 94% protection against symptomatic coronavirus.
Moderna reported this Monday that it plans to comply with the delivery schedule of its vaccines agreed with the Government, to which it has provided 100 million doses so far and plans to deliver another 100 million by the end of May and 100 million more by the end of July. .