The vaccinations are an important weapon in the fight against the coronavirus and its mutants.
Therefore, manufacturer Moderna adapted its vaccine and delivers good study results.
The corona pandemic is still in full swing in Germany, but the vaccination campaign is also in full swing. According to the Robert Koch Institute, 268,787 vaccine doses have now been administered. This means that 7,813,381 people, or 9.4 percent of the total population, are fully vaccinated (as of May 9). With this in mind, the federal government passed an ordinance that gives fully vaccinated and convalescents * more freedom.
But how well does the vaccination work against the rampant and diverse corona variants?
This has not yet been scientifically clarified.
However, the researchers came to another surprising finding: According to a study, Covid-19 should not be a respiratory disease, but a vascular disease *, as
reported by echo24.de
*.
But back to the vaccine.
According to reports, the US manufacturer Moderna is said to have adapted its vaccine to the mutated variants.
In the fight against corona mutants: US manufacturer Moderna adjusts its vaccine
The coronavirus hit the world hard and sparked a pandemic.
But above all the scientists did not stand idly by as the world sank into chaos and set about developing a vaccine.
Now, for over a year with the coronavirus, there are some vaccines against the virus on the market.
To prove the effectiveness of the vaccine, countless studies have been published - including on side effects.
Manufacturer / developer |
Moderna, NIAID |
Research name |
mRNA-1273 |
Type of vaccine |
RNA |
Application form |
Intramuscular injection |
A study from Great Britain is intended to provide important information on cerebral vein thrombosis in connection with mRNA vaccines * from Biontech and Moderna.
So far, however, there are only a few studies that the existing vaccines are also effective against the corona mutants.
The US manufacturer Moderna has therefore reacted in good time and adapted its vaccine to the South African variant and published the first promising study results.
Adapted corona vaccine: study delivers good results
According to a clinical study, the adapted vaccine achieved good results, reports
n-tv.de
. It boosted the production of antibodies that could protect vaccinated people from the South African mutation. This was announced by a research group on the preliminary results. It is also possible that the modified vaccine could also protect against the Brazilian variant.
"While we try to defeat the ongoing pandemic, we remain determinedly proactive if the virus evolves," said Stéphane Bancel, CEO of Moderna, according to a statement from the company.
“We are encouraged and confirmed by these new data that our booster strategy protects against these newly discovered variants.” But how did the researchers come to these promising study results?
Study on corona variants: study participants already vaccinated - protection against three variants
As
n-tv.de
further reports, the adapted vaccine is said to have been tested on study participants who have already received both doses of the conventional Moderna vaccine. The researchers found that the majority of the participants had developed good defense levels against the original form of the coronavirus. However, the immunity against the South African variant B.1.351 and the Brazilian mutant P.1 left something to be desired. In half of those tested, it was even below the detection limit. This means that the original vaccine can only provide limited protection against the two mutations.
Before the third vaccination, the subjects were divided into two groups.
Accordingly, one group of participants received a booster with the modified vaccine, the other group received the original vaccine again.
After this third dose, there was an increase in neutralizing antibodies against all variants of the coronavirus.
The modified vaccine against the South African variant achieved the best results.
A third vaccination with the conventional vaccine, on the other hand, showed somewhat better results in the formation of antibodies directed against the P.1 variant.
Corona variants: study results - good protection after third vaccination?
It remains to be seen whether the modified Moderna vaccine actually works better against the coronavirus variants. The results of the study could also indicate that a third vaccination with the conventional vaccine from the manufacturer Moderna can provide good protection against the two mutations of concern. Overall, the tolerability of the adapted vaccine was rated as good.
* echo24.de is an offer from IPPEN.MEDIA.