Hong Kong’s new crown vaccination plan has been implemented for nearly half a year. Research by the Hong Kong Sanatorium and Hospital shows that the levels of antibodies and alternative neutralizing antibodies of medical staff who vaccinated Forbitai or Kexing vaccine have fallen sharply after three months, but Fubitai The vaccine has a higher level of antibodies.
Experts point out that antibodies are just one of the tools to defend against viruses, and they will inevitably decline over time. "There is no longer a virus antigen in the body, and antibodies will continue to be produced, which is not cost-effective." Once a virus invades, it relies on memory cells to quickly. An immune army is produced, so a drop in antibody levels does not mean that the vaccine is ineffective, and serious complications and even death after being recruited can still be avoided.
▼On October 21, the "Hong Kong Community Anti-epidemic Connection" held regional vaccination activities for two consecutive days▼
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In the previous injection study by the Sanatorium and Hospital recruited medical staff, 197 people were vaccinated with Kexing vaccine and 100 people were vaccinated with Bitel vaccine. 12 weeks after their second dose, most of the people tested positive for antibodies.
However, the antibody level dropped rapidly over time. The median antibody IgG level of Kexing vaccine reached 721.3AU/mL two weeks after the completion of the second injection, and fell to 253.6AU/mL at the 12th week; the Fubitai vaccine reached 9704.15AU at the second week. /mL, it fell to 2840.25AU/mL at the 12th week, which was 11 times the antibody level of the Kexing vaccine at the 12th week.
99% of people in Fubitai still get alternative neutralizing antibodies after 12 weeks
In terms of the level of alternative neutralizing antibodies, 94.4% of people who received the second shot of Kexing vaccine tested positive within two weeks, but it fell to 62.4% by the 12th week; 100% of the people who received the Fubitai vaccine tested positive in two weeks. It was positive, 99% of people still tested it at the 12th week.
According to the study, 222 people still got the replacement neutralizing antibody 12 weeks after the two injections because they were younger.
Liang Zichao pointed out that antibodies will inevitably decline over time, but there is still assistance such as memory cells.
(Data Picture/Photo by Tan Weiquan)
Liang Zichao: The body does not constantly produce antibodies
Liang Zichao, a specialist in respiratory system, said that the decline of antibody levels over time is inevitable. "There will be no more viral antigens in the body, and antibodies will continue to be produced. It is not cost-effective." Even the antibodies produced after natural infections will also When it falls, society does not need to over-deduct, and don’t think that vaccines are useless because of this.
Memory cell protection is more important after vaccination
He said that in addition to antibodies, the more important thing is the protection of memory cells. When a virus strikes, memory cells in the body will quickly produce new troops to cope with it. There are serious symptoms", but it is not easy to measure the level and response of memory cells, so it is rarely mentioned in the society.
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