The latest research from the Chinese University of Medicine School of Medicine found that 76% of patients who recovered from the new crown will continue to experience poor memory, hair loss and fatigue, commonly known as "long new crown" sequelae (that is, patients have persistent symptoms after being infected with the new crown virus for weeks to months). It is shown that the imbalance of intestinal bacteria after the patient is closely related to the risk of "long new crown", and the lack of intestinal bacteria that can improve human immunity, including Bifidobacterium adolescentis, Bifidobacterium longum and Bifidobacterium pseudominis, is the key , researchers believe that by regulating the bacteria in the gut, it can promote the recovery of patients and reduce the appearance of new coronary pneumonia sequelae.
The CUHK Faculty of Medicine team found that the imbalance of gut bacteria in patients with new coronary pneumonia is closely related to the risk of "long-term new crown". More than 75% of new coronary pneumonia patients will continue to experience symptoms such as poor memory, hair loss and fatigue.
(Provided by CUHK)
"Long new crown" refers to patients with new coronary pneumonia who have at least one symptom for four weeks or more after the virus has cleared.
A study by the Faculty of Medicine at CUHK analyzed the conditions of 106 COVID-19 patients and found that up to 76% of COVID-19 patients developed at least one symptom within 6 months of recovery. The most common symptoms included fatigue (31%), poor memory (28%), and hair loss. (21%), anxiety (21%) and difficulty sleeping (21%).
Intestinal microecological imbalance leads to "long new crown"
The research team found that the intestinal microecology of patients with "long-term new crown" was abnormal, with significantly fewer "good bacteria" and more "bad bacteria"; on the contrary, the intestinal microecology of people without sequelae was richer and more diverse. Similar to people who have never been infected.
The team also found that the "long new crown" patients were no different from those without sequelae in terms of age, gender, other diseases, use of antibiotics and antiviral drugs, and the severity of infection with new coronary pneumonia. The main reason for the "long new crown".
Schematic diagram of the relationship between the intestinal microecology and the "long new crown".
(Provided by CUHK)
Patients lack immune-boosting gut bacteria
The research team further investigated the association between gut bacterial imbalances and different categories of COVID-19 sequelae, including respiratory, nervous, digestive, skin (hair loss), musculoskeletal, and fatigue.
It was found that as many as 81 kinds of intestinal bacteria are associated with various sequelae of the new crown, and many of them are closely related to three or more persistent symptoms.
The team also found that there are several intestinal bacteria that can improve human immunity in the intestines of "long new crown" patients, including Bifidobacterium adolescentis, Bifidobacterium longum and Bifidobacterium pseudominis. The ecological imbalance is the main factor leading to the emergence of "long new crown" in the future.
Regulate intestinal bacteria to promote recovery and reduce sequelae
Chen Jialiang, Dean of the Faculty of Medicine and Director of the Center for Intestinal Microbiome Research at CUHK, said that the results of the study show that the gut microbiome of patients with COVID-19 can predict the risk of sequelae. Regulating the bacteria in the intestinal tract can promote the recovery of patients and reduce the sequelae of new coronary pneumonia.
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