In the past two years, a new coronary pneumonia has proved the rapid and effective application of messenger RNA (mRNA) to vaccines.
China, which originally mainly relied on inactivated vaccines for epidemic prevention, has recently launched the development of domestic mRNA new crown vaccines.
At the same time, mRNA vaccine manufacturers such as BioNTech and Moderna are already researching more applications of this technology beyond Covid-19, and have recently achieved preliminary positive results in the treatment of cancer.
How will mRNA technology set off a medical revolution?
On January 11, 2020, Professor Zhang Yongzhen of Shanghai Public Health Clinical Center and School of Public Health of Fudan University shared the genetic sequence of the new coronavirus (SARS-CoV-2) to the world.
In March of the same year, the World Health Organization (WHO) declared COVID-19 a pandemic.
On the 16th of the same month, the world's first mRNA vaccine jointly developed by the National Institutes of Health (NIH) and Moderna has started the first phase of clinical trials.
Recently, BioNTech published a study using mRNA technology to cooperate with CAR-T therapy to fight cancer, and the preliminary results were positive.
The picture shows the Pfizer/BioNTech new coronary pneumonia vaccine.
(Associated Press)
Only 11 months after the viral gene sequence was made public, the U.S. Food and Drug Administration (FDA) approved the use of the mRNA COVID-19 vaccine developed by Pfizer/BioNTech on December 18 of the same year with an efficacy of 95%. The fastest vaccine.
Dragony Fu, an associate professor at the Department of Biology at the University of Rochester, UK, described this as the application of "mRNA vaccine 1.0", and we are entering the era of "mRNA 2.0".
Katalin Karikó, an mRNA expert and senior vice-chairman of BioNTech, recalled that when she first held the mRNA academic conference in 2013, no one among the participants expected that an mRNA vaccine that could be approved by the FDA would appear within ten years.
Unexpectedly, mRNA technology became famous in an epidemic.
In fact, Karikó's original intention when he started researching mRNA technology many years ago was not to create vaccines, but to direct the body to produce specific proteins for therapeutic purposes...
For details, please read the 314th issue of "Hong Kong 01" Electronic Weekly Newsletter (April 25, 2022) "
New Coronary Pneumonia Unleashes mRNA Revolution The Next Step Is Cancer Treatment?
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