It is feared that there are missing people in Cantiano, a town of just over 2,000 inhabitants, hit by a water bomb that transformed the streets into real streams and dragged away cars.
These are not missing persons, but who have not been traced at the moment.
The phones don't work and the mayor Alessandro Piccini has launched an appeal via social media, inviting citizens to stay at home.
In some areas the water has reached the first loaves.
The Contessa pass closed.
Several rivers overflowed, including the Burano.
"A water bomb is hitting Cantiano - the mayor's alarm -. Several rivers have overflowed. The water has invaded the central streets of the town. Several areas are already submerged. The municipal road network is interrupted in several sections. The state road towards Gubbio is closed. We invite citizens to remain calm and avoid risky situations ".
Firefighters and carabinieri intervened on the site.
Another emergency was reported in Pergola, also in the province of Pesaro Urbino, where a family took refuge on the top floor of a house and asked for help.