His disappearance is considered worrying by the police.
A call for witnesses has been launched on social networks to try to find Jessica Amisoi in the Côtes-d'Armor.
The 12-year-old girl left the family home in Saint-Brieuc on Saturday afternoon and has not returned home since.
The teenager has black curly hair, black eyes and is 1.55m tall.
It is not known, however, what clothing she was wearing at the time of her escape.
Anyone who can advance the investigation is invited to contact the Saint-Brieuc police station as soon as possible at 02.96.77.29.00.
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