Spying on what happens in the microscope of the world of cells without damaging them: this is the goal of Micro4Pap, the European project coordinated by the Italian Institute of Technology, with Giancarlo Ruocco and Gian Gaetano Tartaglia as coordinators, and funded with more than 3 million by the European Innovation Council for the development of a new generation microscope useful for the study of different pathologies, such as neurodegenerative disorders.
Simplified name of In-Vivo Brillouin Microscope with application to Protein Aggregation-based Pathologies, the Micro4Pap microscope that will be born from the European project aims to allow live observation of what happens inside living cell tissues, without altering their functionality or destroying the sample. It is a type of Brillouin microscope with rapid scanning, with acquisition times of less than a millisecond, which will allow to observe in 3D the various cellular components.
The new microscope does not need to come into direct contact with the samples to be analyzed and is therefore ideal for observing the internal dynamics of cells and between cells. Since the alteration of these processes is the basis of many human diseases, from neurodegenerative disorders to cancer to chronic diseases and those related to aging, the new microscope will provide important indications for the development of new drugs, early diagnosis and future new therapies. For its development, the EIC has allocated 3 million euros to the Micro4Pap consortium coordinated by IIT and which includes research institutes, universities and companies in Italy (University of Trento and Crestoptics S.p.A.), the University of Angers in France and the University of Zaragoza in Spain.
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