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Revolution in cancer diagnostics: Researchers develop “groundbreaking” capsule test

2024-04-04T17:07:57.987Z

Highlights: Revolution in cancer diagnostics: Researchers develop “groundbreaking” capsule test. If esophageal cancer is detected early with the cancer test, surgery may be sufficient. In Germany, around 6,100 men and 1,800 women suffer from it every year. The test was developed by Rebecca Fitzgerald, director of the Early Cancer Institute at the University of Cambridge. The project was commissioned by the English National Health Service (NHS) It is intended to relieve endoscopy capacity.



As of: April 4, 2024, 6:59 p.m

By: Teresa Toth

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Some types of cancer can only be detected late - a cure is often no longer possible. Researchers have now developed a new cancer test.

Cambridge – Cancer is the second most common cause of death in Germany. There is still a lack of treatment options. However, there may be a vaccine against cancer in the future. Until then, early detection of cancer is crucial for a successful cure. However, the disease is often only discovered when it is already too late. A newly developed cancer test could now change that.

Esophageal cancer is often only detected at a late stage. © Andrey Popov/dpa

New cancer test for earlier detection of esophageal cancer

A pilot project at the University of Cambridge examined over 8,500 patients using the so-called “capsule sponge test,” as reported on the university website. This test aims to detect the risk of esophageal cancer. Although this type of cancer is relatively rare in Germany, as the German Cancer Society explains, it is often only detected at an advanced stage, which significantly reduces the chances of recovery.

esophageal cancer

Esophageal cancer can occur anywhere in the esophagus. Common symptoms include gagging when eating, esophageal spasms, and heartburn and hoarseness. In Germany, around 6,100 men and 1,800 women suffer from it every year.

Source: German Cancer Society

As part of the test, patients were asked to swallow a small capsule containing a tiny sponge. This sponge collected cells from the esophagus. Using a thread attached to the capsule, it could be pulled out again. Using the cell samples collected, researchers were able to determine whether the patients had Barrett's esophagus, a disease of the esophagus that can lead to cancer. The test was developed by Rebecca Fitzgerald, director of the Early Cancer Institute at the University of Cambridge.

Cancer test is intended to relieve endoscopy capacity

Barrett's esophagus could previously only be diagnosed through an endoscopy. The evaluation of the test showed that one or two of the patients tested had corresponding cells. These patients were referred to endoscopy for further diagnostics, while all other test participants were discharged. Various early detection methods already exist for other types of cancer.

Fitzgerald describes the positive results of the test as “very exciting.” They could help to relieve endoscopy capacity. With the new cancer test, an increased risk of esophageal cancer can be determined in advance. This would allow unaffected patients to be discharged and affected patients to be referred to endoscopy more quickly.

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If esophageal cancer is detected early with the cancer test, surgery may be sufficient

The project was commissioned by the English National Health Service (NHS). Amanda Pritchard, NHS chief executive, highlighted: “The NHS is always looking to introduce the latest innovations and new ways of working that help improve patient experiences and increase efficiency – this simple sponge-on-a-string test is just one Example of many groundbreaking instruments that we have tested in recent years to be able to diagnose and treat people more quickly.” A new cancer drug could also be promising in curing cancer.

The German Cancer Society points out that the chances of recovery increase significantly if esophageal cancer is detected early. If the cancer is still limited to the mucous membrane, it can usually be operated on without any problems. Dr. Danielle Morris, a specialist in gastroenterology, is also enthusiastic about the new cancer test: “The use of the capsular sponge test as a diagnostic tool has brought enormous benefits to patients: (...) the waiting lists for endoscopy have been shortened, so we are the one Those who really need an endoscopy can have it delivered quickly.”

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Source: merkur

All news articles on 2024-04-04

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