Thanks to goals from Toko Ekambi (32nd) and Dubois (92nd), Lyon won on the wire against Bordeaux (2-1), at the start of the 22nd day.
Kalu had equalized for the Girondins (55th).
Dubois's magnificent goal allows the Rhone residents to temporarily regain the lead in Ligue 1 ahead of PSG and Lille.
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League 1 standings