New tile for Paulo Dybala.
The Juventus striker is forfeited for the match on Lazio's lawn this Saturday.
In question, a muscular fatigue on a calf that he contracted during the international break with the Albiceleste.
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In addition to his main attacking danger, coach Massimiliano Allegri is deprived, for this post-international cut, of Italian internationals Giorgio Chiellini (thigh) and Federico Bernardeschi (hip) and Welsh midfielder Aaron Ramsey (thigh).
Juventus assured Thursday that Dybala, 28, did not suffer from an injury but had confirmed muscle fatigue which also deprived him of Argentina's match against Brazil (0-0) on Tuesday.
Without the Argentina international, Allegri could field an attacking duo Federico Chiesa-Alvaro Morata on Saturday on the lawn of the Stadio Olimpico.
Lazio Rome could also come in with a weakened attack, as uncertainty still hangs over the presence of home scorer Ciro Immobile.
The best scorer of Serie A (10 goals), affected in a calf, had to give up the two matches of Italy during the qualifications for the World-2022.
Lazio is currently 5th, three points ahead of Juventus (8th, 18 pts).