Benoît Paire will not see the second week of competition in Melbourne.
The Frenchman was eliminated in the round of 16 by Stefanos Tsitsipas in four sets (6-3, 7-5, 6-7, 6-4) and despite good resistance.
Tsitsipas will face Taylor Fritz for a place in the quarter-finals, the American having overcome Roberto Bautista Agut in five sets.
To discover
Australian Open: men's schedule and results
Australian Open: ladies schedule and results