It will be without Ousmane Dembélé.
Usually a starter in PSG's attacking right lane, the world champion is not in the group to play the match in Strasbourg this Friday at Meinau counting for the 20th day of Ligue 1.
His package adds to the known absence of Bradley Barcola, suspended after his expulsion against Brest (2-2) last week at the Parc des Princes.
The former Barcelona player is left to rest as a precaution, he suffers from a slight muscle discomfort without seriousness.
Without the two wingers regularly aligned in recent weeks, Luis Enrique could opt for Randal Kolo Muani and Marco Asensio around Kylian Mbappé.
The three will travel to Alsace along with 17 other players selected by the Spanish coach such as Gianluigi Donnarumma, Keylor Navas, Arnau Tenas, Lucas Beraldo, Marquinhos, Nordi Mukiele, Gonçalo Ramos and the young Ethan Mbappé, Senny Mayulu, Yoram Zague, right back and captain of the U19s.
Leader with six points ahead of Nice, Paris faces 10th-placed Strasbourg, which remains on a good dynamic.
Without Ousmane Dembélé, Marquinhos' partners will experience creative difficulties, like their performance against Brest.
It was Randal Kolo Muani who was preferred in his place, with a notable deficit in his tactical and technical performance.
A new chance is offered to him this Friday with the withdrawal of the right attacker, who only came into play in the 69th minute against the Bretons last Sunday.