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From Google's AI the portrait of all human proteins

2021-07-23T08:49:10.589Z

A new era in biology opens thanks to the more complete and accurate 'portrait' of proteins in the human body, created by the AlphaFold artificial intelligence developed by Google's DeepMind (ANSA)



A

new era in biology

opens

thanks to the

more complete and accurate 'portrait' of proteins

in the human body: this was created by the

AlphaFold

artificial intelligence system

, developed by the British company

DeepMind

from

Google

, which managed to predict the 3D structure of

20,000 proteins

expressed by the human genome, in addition to those of 20 other organisms (from the mouse to the malaria parasite) crucial for research. The results, published in the journal Nature, are collected in a

database

that in collaboration with the European Molecular Biology Laboratory (EMBL) is made freely accessible to scientists from all over the world, to

accelerate research

in the life sciences, to

develop new drugs

and

make the most of the planet's resources

.



The database greatly increases the knowledge gained so far, more than

doubling

the number of human protein structures predicted with great accuracy. Previously, it was possible to determine the exact location of

17%

of the amino acids that make up human proteins: this result was achieved with decades of particularly long and complex laboratory studies and experiments. Artificial intelligence, on the other hand, managed in a few months to predict the position of 58% of amino acids with a good margin of certainty:

35.7%

was localized with a very high degree of confidence, practically double what was obtained experimentally. .

"This will be one of the most important datasets from human genome mapping," says EMBL Deputy Director General and EMBL-EBI Director Ewan Birney. "Making AlphaFold predictions accessible to the international scientific community opens up many new avenues of research, from neglected diseases to new enzymes for biotechnology and much more. It is a great new scientific tool, which complements existing technologies, and will allow us to broaden the boundaries of our understanding of the world ".

Source: ansa

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