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Penicillin: the first patient, miraculously then died… for lack of doses

2022-07-04T09:05:08.214Z


HISTORY OF MEDICINE - Even once clearly demonstrated its effectiveness and non-toxicity, the difficulties in purifying the substance from molds has slowed down the generalization of its use.


“Other Observations on Penicillin.”

Is this, then, British phlegm?

On August 16, 1941, in these words of absolute sobriety, a team of Oxford researchers described in

The Lancet

nothing less than… the very first use of antibiotics in humans.

Either one of the main medical revolutions of the


20th century!

In 1939, more than ten years ago Alexander Fleming isolated penicillin and demonstrated its antibacterial action.

He is not quite the first, but the difficulties in purifying the substance from molds, and the (relative) success of sulfonamides, relegate to anonymity the results published by the London university in the

British Journal of Experimental pathology

.

At least until the German chemist, Ernst Chain, and the one who recently recruited him at Oxford, the Australian professor of pathology Howard Florey, became interested in it.

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They want to test this promising substance, but first they have to successfully extract and…

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Source: lefigaro

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