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Chronic pain: the effectiveness of antidepressants questioned

2023-05-21T15:18:58.921Z

Highlights: In France, chronic pain, such as neuropathic, musculoskeletal pain or fibromyalgia, affects 1 in 5 people. Opioid medications are not recommended, not only because of the risk of addiction, but also because they are not effective. Doctors had found an alternative with antidepressants. In addition to their effects on anxiety, these drugs would indeed have a specific analgesic action. However, their effectiveness has just been called into question by an analysis of studies conducted by Cochrane.


In addition to anxiety, antidepressants are increasingly prescribed for chronic pain. Their effectiveness is questioned.


In France, chronic pain, such as neuropathic, musculoskeletal pain or fibromyalgia, affects 1 in 5 people. These are particularly difficult pains to manage. Opioid medications are not recommended, not only because of the risk of addiction, but also because they are not effective.

Doctors had found an alternative with antidepressants. In addition to their effects on anxiety, very common in case of chronic pain, these drugs would indeed have a specific analgesic action. Antidepressants are therefore increasingly prescribed in the context of chronic pain.

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However, their effectiveness has just been called into question by an analysis of studies conducted by Cochrane, a collaborative database that regularly publishes reference work to summarize the state of knowledge on a given medical topic.

Read alsoChronic pain: why (and how) to consult in a pain center?

Here, the authors have compiled 176 studies carried out out on a total of some...

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Source: lefigaro

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